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雷贝拉唑三联疗法治疗消化性溃疡效果观察 被引量:2

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摘要 目的观察雷贝拉唑与法莫替丁治疗消化性溃疡(peptic ulcer,PU)和幽门螺杆菌(H.pylori,HP)根除率比较以及药物的副作用。方法随机将64例PU患者分为两组。观察组:口服雷贝拉唑20 mg,克拉霉素500 mg,阿莫西林1 000 mg,均每日2次,治疗1周;7 d后服用雷贝拉唑20 mg,每日1次,治疗3周。对照组:法莫替丁20 mg,克拉霉素500 mg,阿莫西林1 000 mg,均每日2次,治疗1周;7 d后服法莫替丁20 mg,每日2次,疗程3周。结果治疗组与对照组溃疡愈合率分别为90.62%和53.12%,两者比较有显著差异(P<0.05)。HP根除率分别为84.37%和56.25%,两者比较有显著差异(P<0.05)。结论雷贝拉唑三联疗法对PU治疗及根除HP具有良好的疗效。
作者 彭建中
出处 《湘南学院学报(医学版)》 2008年第2期44-46,共3页 Journal of Xiangnan University(Medical Sciences)
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