摘要
本研究通过动物实验探讨了祛膜汤加强抗旱孕的作用机理。实验表明：与米非司酮组和对照组比较，加用祛膜汤1ml组早导大鼠第10天、第13天血浆孕酮含量显著降低（P＜0．05）。祛膜汤对动情前期和早孕期大鼠离休子宫肌收缩强度和张力均有不同程度的增强作用，并能使家兔在体子宫内压升高，宫缩频率增加。结果初步提示祛膜汤可能通过降低血浆孕酮水平，增强子宫肌收缩的作用，从而在临床上能提高完全流产率。
The studies investigated the efficacy and mechanism of QMT for termination of early pregnancy and treatment of heavy vaginal bleeding after medicinal abortion.The animal experiments shoWed that, in comparison with those in Mifepristone group (group B) and control group (group A), plasma progesterone levels decreased significantly in early pregnant SD rats in QMT group (Mifepristone+QMT, group C). In addition, QMT increased muscle contraction and tension of uterus in varying degrees in early pregnant SD rats and the SD rats during pre-estrus phase. QMT also increased the intrauterine pressure and contraction frequency of the rabbit uterus in vivo.Dilatation occurred in two-thirds of rats in group B, while significantly contraction in all rats of group C, as indicated by microscope observation.The results indicated that QMT increase the complete abortion rate in clinic by reduced plasma progesterone levels and increased uterine muscle contraction.
出处
《生殖与避孕》
CAS
CSCD
北大核心
1997年第6期347-353,共7页
Reproduction and Contraception
关键词
祛膜汤
避孕
中药
Termination of early pregnancy, QMT, Plasma progesterone, Uterine contraction
