摘要
目的:探讨早期内镜治疗急性胆源性胰腺炎(acute biliary pancreatitis,ABP)患者的疗效.方法:将确诊为ABP的86例患者,随机分为内镜组(n=42)、传统治疗组(n=46),对比分析两组患者白细胞、肝功能及血淀粉酶恢复时间,腹痛缓解时间,住院天数,并发症发生率及死亡率.结果:内镜组与传统组相比,白细胞恢复时间(9.7±2.6d vs 13.3±3.9d,P<0.05)、肝功能恢复正常时间(12.5±5.1d vs 21.3±6.5d,P<0.05)、血淀粉酶恢复时间(8.2±2.1 vs 12.5±3.3,P<0.05)、腹痛腹胀缓解时间(7.7±2.7d vs 11.4±3.7d,P<0.05)、住院天数均明显缩短(16.1±5.1d vs 23.3±7.6d,P<0.05);总并发症均降低(12.5% vs 23.8%,P<0.05),总死亡率与传统组相比差异无统计学意义.结论:早期内镜治疗ABP,微创、安全、疗效确切,应大力推广.
AIM： To investigate the superiority of endoscopic treatment for senile acute biliary pancreatitis （ABP）. METHODS： Eighty-six ABP （including severe ABP） patients over 60 years were randomly divided into two groups receiving endoscopy （n = 42） and traditional therapy （n = 46） respectively. The therapeutic effects （Recovery time of WBC, hepatic function and hemodiastase, remission time of bellyache, hospitalization time, complication rate and death rate） were comparatively analyzed between the two groups. RESULTS： Recovery time of WBC, hepatic function and hemodiastase were signifi cantly shorter in endoscopic treatment group than traditional therapy group （9.7 ± 2.6 d vs 13.3 ± 3.9 d, 12.5 ± 5.1 d vs 21.3 ± 6.5 d, 8.2 ± 2.1 vs 12.5 ± 3.3 respectively, all P 〈 0.05）, and remission time of bellyache was shorter too in endoscopic treatment group（7.7 ± 2.7 d vs 11.4 ± 3.7 d, P 〈 0.05）. Hospitalization time was markedly shortened in treatment group （16.1 ± 5.1 d vs 23.3 ± 7.6 d, P 〈 0.05）. The total complication rate was significantly lower in endoscopic group than traditional therapy group（12.5% vs 23.8%, P 〈 0.05）, but no statistical signifi cance of total death rate was observed between the two groups. CONCLUSION： Endoscopic treatment for senile ABP is safe, effective and minimally invasive, and is recommended for wide use.
出处
《世界华人消化杂志》
CAS
北大核心
2008年第18期2065-2068,共4页
World Chinese Journal of Digestology
关键词
老年
急性胆源性胰腺炎
内镜
Senium
Acute biliary pancreatitis
En-doscopy
Endoscopic retrograde cholangiopancrea-tography
