期刊文献+

氨溴索治疗慢性阻塞性肺疾病急性发作40例

在线阅读 下载PDF
导出
摘要 目的探讨氨溴索注射液在慢性阻塞性肺疾病(COPD)急性发作中的治疗作用。方法将COPD急性加重期患者70例分为两组。对照组30例仅给予抗生素及解痉平喘药物治疗,治疗组40例加用氨溴索注射液30mg静脉滴注,连用7d。结果两组治疗7d时症状均较治疗前有所好转,但总有效率治疗组(80.00%)较对照组(63.33%)明显要高(P<0.05)。结论氨溴索可有效改善COPD急性加重期患者的症状。
作者 王剑虹 王曦
机构地区 贵州省遵义医院
出处 《中国药业》 CAS 2008年第15期74-74,共1页 China Pharmaceuticals
  • 相关文献

参考文献5

二级参考文献22

  • 1有创-无创序贯机械通气多中心研究协作组.以肺部感染控制窗为切换点行有创与无创序贯机械通气治疗慢性阻塞性肺疾病所致严重呼吸衰竭的随机对照研究[J].中华结核和呼吸杂志,2006,29(1):14-18. 被引量:280
  • 2[1]Gillissen A, Nowak D. Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy. Respir Med, 1998, 92:609-623.
  • 3[2]Teramoto S, Suzuki M, Ohga E, et al. Effects of ambroxol on spontaneous or stimulated generation of reactive oxygen species by bronchoalveolar lavage cells harvested from patients with or with-out chronic obstructive pulmonary diseases. Pharmacology,1999, 59:135-141.
  • 4[3]Gillissen A, Bartling A, Schoen S, et al. Antioxidant function of ambroxol in mononuclear and polymorphonuclear cells in vitro. Lung, 1997, 175:235-242.
  • 5[4]Park NH, Han ES, Lee CS, et al. The inhibitory effect of ambroxol on respiratory burst, de granulation and cytosolic Ca2+ change in degraded immunoglobulin G-activated neutrophils. Pharmacol Toxicol, 1999, 84: 81-87.
  • 6[5]Pfeifer S, Zissel G, Kienast K, et al. Reduction of cytokine release of blood and bronchoalveolar mononuclear cells by ambroxol. EurJ Med Res, 1997, 2:129-132.
  • 7[6]Stettner S, Ledwozyw A. The effect of Ambroxol on bleomycininduced changes in phospholipid composition of rat lung surfactant. Acta Physiol Hung, 1995, 83:181-187.
  • 8[7]Mira E, Benazzo M, De Paoli F, et al. Surfactants of the air-ways. Critical review and personal research. Acta Otorhinolaryngol Ital, 1997, 17(1 Suppl 56):3-16.
  • 9[8]Nemcekova E, Nosalova G, Franova S. Ambroxol and protective reflexes of the respiratory tract. Bratisl Lek Listy, 1998, 99:111-115.
  • 10[9]Tyrakowski T, Greczko Ⅰ, Sedlaczek A, et al. Electrophysiological investigation of the effects of ambroxol on the transepithelial Na + ion transport pathway in airways. Pol J Pharmacol,1998, 50:31-38.

共引文献8589

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部