摘要
采用原料芴经硝化、还原反应得到2-氨基芴,再与一系列的芳香醛缩合得到相应的席夫碱类化合物。其结构经IR、1H NMR、MS和元素分析测试技术得到确证。体外抗菌活性结果表明,大多数化合物具有较好的抑菌活性。
2-Aminofluorene was synthesized via the nitration and reduction of fluorene. The condensations of 2-aminofluorene with a series of aldehyde gave the corresponding sehiff bases （a - h） , and their structures were confirmed by IR, ^1H NMR, MS and elemental analysis. The antibacterial activity was preliminarily evaluated, the results demonstrate that most of the compounds prepared displayed potential antibacterial activity.
出处
《应用化学》
CAS
CSCD
北大核心
2008年第8期980-982,共3页
Chinese Journal of Applied Chemistry
基金
湖北省高等学校优秀中青年科技创新团队计划资助项目(T200707)
关键词
氨基芴
席夫碱
合成
抗菌活性
aminofluorene, Schiff base, synthesis, antibacterial activity
