摘要
１日龄雏鸡人工感染ｖＭＤＶ，并注射黄芪多糖（ＡＰＳ）和香菇多糖（Ｌｅｎ），分别于７、１６、２８、４２和５６日龄检测雏鸡淋巴细胞化学发光（ＣＬ）的变化。结果表明：（１）ＡＰＳ对７、１４日龄ｖＭＤＶ感染雏鸡胸腺、脾脏和法氏囊淋巴细胞的ＣＬ有显著抑制作用（ｐ＜０．０５，ｐ＜０．０１），在２８、４２日龄则显著增强淋巴细胞ＣＬ（ｐ＜０．０５，ｐ＜０．０１）；（２）Ｌｅｎ对７、１４日龄ｖＭＤＶ感染雏鸡胸腺、脾脏淋巴细胞ＣＬ值升高有显著抑制作用（ｐ＜０．０５，ｐ＜０．０１），２８和４２日龄时有显著增加作用（ｐ＜０．０５，ｐ＜０．０１），但整个期间对法氏囊淋巴细胞ＣＬ值影响不大（ｐ＞０．０５）。结果提示，ＡＰＳ和Ｌｅｎ抗ＭＤ及其肿瘤的生物效应可能与其调节淋巴细胞氧自由基代谢有关。
nedayold broiler chicks artificiallyinfected with vMDV,were injected with APS or LenThe CL of lymphocytes in chicks was detected at 7,14,28,42 and 56 days after treatmentThe results showed:(1)APS suppressed CL of lymphocytes isolated from the thymus,spleen and bursa of Fabricius significantly(p<005,p<001)at 7,14 days after treatment,whereas enhanced CL significantly (p<005,p<001)at 28,42 days;(2)Len suppressed CL of lymphocytes isolated from the thymus,spleen significantly(p<005,p<001)at 7,14 days,where as enhanced CL sipnificantly(p<005,p<001) at 28,42 days,however no signtificant effect on CL of bursa hymphocytes was observedThese results suggest the biological effect of APS and Len on antiMD or MD tumor is related to their regulation on active oxygen radical metabolism of hymphocytes in chicks
出处
《畜牧兽医学报》
CAS
CSCD
北大核心
1997年第6期542-546,共5页
ACTA VETERINARIA ET ZOOTECHNICA SINICA
基金
国家自然科学基金
