摘要
根据溶栓治疗后梗塞相关冠状动脉获开通的时间不同，将５９例急性心肌梗塞（ＡＭＩ）病人分为＜６小时组和＞６小时组，又根据溶栓后冠状动脉造影显示的冠状动脉通畅的程度不同，分为通畅组、基本通畅组和未通组，观察梗塞相关血管开通的不同时间和不同程度对心肌梗塞近期预后的影响。结果发现，６小时内开通者可明显降低心肌梗塞面积，改善梗塞后左室功能以及减少并发症的发生，＞６小时开通组与未通组相比，也有一定程度缩小梗塞面积和减少并发症的作用；基本通畅组近期心律失常、心绞痛以及再梗塞率高于通畅组和未通组，但基本通畅组和通畅组心肌梗塞缩小面积差异无显著性。提示ＡＭＩ后梗塞相关血管及时有效再灌注有利于改善心肌梗塞的近期预后。
The aim of the study was to investigate the effect of rapid and effective reperfusion of infarctrelated coronary artery on the early prognosis of acute myocardial infarction after intravenous thrombolytic therapy. 59 patients were studied. Coronary angiography was performed 60 to 90 minutes after intravenous thrombolysis. According to the different reperfusion time, the patients were divided into <6 hour group and > 6 hour group. The patients were also divided into partial reperfusion (TIMI 2) group, complete reperfusion (TIMI 3) group and nonreparfusion group (TIMI 01), according to reperfusion degree. All patients were received 4 to 5 week followup. As a result, in < 6 hour groups, the infarct area decreased, LVEF after myocardial infarction was higher, and the complications such as angina, ventricular arrhythmia were less than > 6 hour groups. The infarct size was also decreased in > 6 hour groups compared with nonreperfusion group. In partial reperfusion groups, early complication such as angina, ventricular arrhythmia were more common than complete reperfusion groups and even nonreperfusion group. However there was no significent difference in infarct size between partial reperfusion groups and complete reperfusion groups. It is suggested that rapid and effective reperfusion of infarctrelated artery after acute myocardial infarction can improve the early prognosis of acute myocardial infarction.
出处
《中华心血管病杂志》
CAS
CSCD
北大核心
1997年第6期429-432,共4页
Chinese Journal of Cardiology
关键词
心肌梗塞
心肌再灌注
AMI
溶栓疗法
预后
myocardial infarction thrombolytic therapy myocardial reperfusion
