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溴虫腈亚慢性毒性研究 被引量:4

Study on subchronic toxicity of chlorfenapyr in rats
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摘要 按照GB15670—1995《农药登记毒理学试验方法》,以25、50、125 mg/kg剂量的溴虫腈染毒大鼠,以观察其亚慢性毒性。结果125 mg/kg剂量组动物出现明显中毒症状,丙氨酸氨基转移酶(ALT)及白细胞总数(WBC)升高,肝脏脏器系数增大,肝脏病理组织学检查可见明显的组织形态学改变。提示溴虫腈可引起大鼠肝脏损伤,大鼠经口亚慢性最大无作用剂量为25 mg/(kg.d)。
出处 《中国工业医学杂志》 CAS 北大核心 2008年第4期254-256,共3页 Chinese Journal of Industrial Medicine
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