摘要
目的探讨术前用羟乙基淀粉行急性超容血液稀释对胃肠择期手术病人肾功能的影响。方法选择90例ASAⅠ～Ⅱ级的择期胃肠手术病人,随机分成3组:H组(贺斯组)、B组(输血组)和R组(对照组),3组病人均采用静吸复合全麻。H组和B组分别用贺斯、血液术前扩容。结果3组血尿素氮、血肌酐、尿量、尿比重等肾功能常用指标基本在正常范围内;3组血RBP始终在正常范围;而B组尿RBP3呈升高趋势,H组、R组组内比较无统计学意义,B组尿RBP值T1高于T0,有统计学意义(P<0.05)。结论急性超容性血液稀释不影响机体肾功能的稳定;本研究证实新一代人工胶体羟乙基淀粉液(贺斯6%HES200/0.5),扩容效果和维持时间同血液相似,且优于晶体液,能有效维持循环稳定,是一种简单可行、安全有效的血液保护方法。
OBJECTIVE To investigate the effects of acute hypervolemic hemodilution（AHH） with different liquids on renal function in patients undergoing scheduled gastrointestinal surgery. METHODS Thirty patients are ASA Ⅰ～Ⅱ , who were to under go lective opera tion of gastric cancer or rectum cancer. The patients were divided into three groups in random： H group （HES group）, B group （blood group）, R group（Ringers Solution group）. H group, B group were infused HES, Blood seperately to make acute hypervolemic hemodilution. RESULTS ①BUN, Scr and volume of urine are all in the normal range and have no differences in the intergroup comparisons and the within group comparison; ②RBP： sRBP was always in the normal range, but there was no statistical significance in the intergroup comparisons and the within group comparision（P〉0.05）. CONCLUSION AHH had no effect on the stability of Renal function. This study confirmes that the new generation of artificial colloid HES can effectively maintain the hemodynamic in the state of stable. Its volume expansion effect and maintaining time is similar to Blood and is more reliable than that of crystalloidal fluid, therefore, AHH may be as a feasible, safe and effective mothed of saving blood to apply in major surgery.
出处
《中国初级卫生保健》
2008年第9期88-89,共2页
Chinese Primary Health Care
关键词
围手术期
超容血液稀释
肾功能
acute hypervolemic hemodilution, hydroxyethyl starch, renal function
