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胃镜套扎术合用β受体阻滞剂预防与治疗肝硬化食管静脉曲张出血的临床研究 被引量:5

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摘要 目的:探讨内镜下套扎与断流术和药物治疗肝硬化食管静脉曲张破裂出血(EVB)的各自止血效果,从中发现治疗EVB最佳路径。方法:对235例肝硬化食管静脉曲张破裂出血的患者分别进行内镜下食管静脉套扎术(EVL),外科断流术,以及内科药物保守治疗。结果:在预防性出血上EVL+心得安组有效率达到95%,而单纯心得安组为82.5%;在对肝硬化食管静脉曲张破裂出血的患者分别采用了三种不同的治疗方法:EVL治疗有效率为91.57%,食管静脉曲张(EV)的复发率34.94%,再出血率19.28%;断流术组有效率达到96.59%,EV复发率28.13%,再出血率18.75%;而药物组有效率68.75%,EV复发率52.5%,再出血率32.5%。肝功能状态越好,EV复发率、再出血率就越少。采用EVL治疗的乙型肝炎肝硬化69例,使用抗病毒药物的患者EV复发率23.68%,再出血率10.53%;未使用抗病毒药物的患者EV复发率38.71%,再出血率22.58%。结论:EVL+β受体阻滞剂是目前治疗肝硬化食管静脉曲张破裂出血在一级预防和二级预防中最佳的治疗方法,抗病毒治疗可以明显减少复发率,EVL具有疗效好、适应证广、并发症少、费用低等优点。
出处 《内蒙古医学杂志》 2008年第8期973-975,共3页 Inner Mongolia Medical Journal
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