摘要
目的:探讨局部应用富血小板血浆(platelet-rich plasma,PRP)对狗脱位牙再植后牙周组织愈合的影响。方法:将6只Beagle犬的第二切牙拔除,干燥放置60 min,按随机区组设计分为4组,A组为再植前根面及牙槽窝涂布PRP,7 d后行根管充填术;B组为涂布PRP,未行根管充填术;C组为未涂布PRP,7 d后行根管充填术;D组为未涂布PRP,未行根管充填术。12周后进行组织学观察,分别计算每颗牙的正常牙周膜指数(正常牙周膜位点的百分率)和3种吸收指数(3种吸收位点的百分率),结果进行统计学分析。结果:A、C 2组各种吸收指数和正常牙周膜指数差异不明显;B组替代性吸收发生率较D组明显减低,正常牙周膜率则比D组明显增高。结论:在一定条件下局部应用PRP可减少非根管治疗再植牙替代性吸收的发生,并可促进其牙周组织的正常愈合。
Objective：To evaluate the influence of platelet-rieh plasma （PRP） on periodontal healing of replanted teeth in 6 Beagle dogs. Methods ：The second incisors were pulled out and re-implanted after 60 min dry storage. In group A, PRP were applied before replantation, and 7days later the teeth received mot canal treatment. In group B, PRP were applied before replantation either, but without root canal treatment. In group C, PRP were not applied and 7 days later, the teeth received root canal treatment. In group D, no PRP were applied and no root ca- nal treatment. All the dogs were sacrificed after 12 weeks and the histological parameters were observed. Results： There were no significant differences between group A and C. Group B showed a lower incidence of ankylosis, and higher incidence of healed PDL compared with group D. Conclusion：Under the definite condition, PRP can help to decrease the incidence of ankylosis and increase the incidence of healed PDL in groups that the pulps were not removed.
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
2008年第5期659-664,共6页
Journal of Practical Stomatology
基金
福建省科技重大课题基金项目(编号:2001Z021)
福建省卫生厅青年基金项目(编号:2004-1-24)
关键词
富血小板血浆
牙脱位
牙再植
牙根吸收
Platelet-rich plasma （PRP）
Replantation of teeth
Avulsed teeth
Root resorption
