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多层螺旋CT灌注成像技术在孤立性肺结节诊断及鉴别诊断中的应用 被引量:2

Application of muti-slice CT perfusion imaging in diagnosis and differential diagnosis for solitary pulmonary nodules
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摘要 目的:探讨CT灌注成像对孤立性肺结节(SPN)的诊断与鉴别诊断价值。方法:利用美国GE公司的HispeedCT16排螺旋CT灌注的扫描方法对43例SPN患者(有病理诊断38例,20例为恶性结节,8例为炎性结节,10例为良性结节)的肺灌注参数值进行分析,同时对病灶进行时间-密度曲线形态及强化程度的分析。结果:恶性结节的血容量(BV)、平均通过时间(MTT)、表面通透性(PS)均高于炎性结节(P<0.05),而血流量(BF)亦无显著性(P>0.05),而炎性结节的BF、BV、MTT、PS均高于良性结节(P<0.05)。结节的时间-密度曲线(TDC)显示,恶性结节表现为速升缓降型,炎性结节表现为速升速降型,良性结节表现为平缓型(P<0.05)。强化形式,恶性结节多表现为均匀强化或不均匀强化,炎性结节多表现为不均匀强化,良性结节多为不强化(P<0.05)。结论:多层螺旋CT灌注成像既能提供结节的形态学信息,又能提供结节的血流动力学信息,为临床孤立性肺结节的诊断及恰当的治疗提供更可靠的依据。
出处 《吉林大学学报(医学版)》 CAS CSCD 北大核心 2008年第5期890-893,共4页 Journal of Jilin University:Medicine Edition
基金 吉林省科技厅科研基金资助课题(2005118)
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共引文献276

同被引文献15

  • 1袁小东,敖国昆,全昌斌,张静,李红,田媛,秦崇,刘哲,田梅.肺双重血供的CT灌注技术及其应用于肺结核的初步研究[J].中华临床医师杂志(电子版),2011,5(20):5913-5918. 被引量:22
  • 2张金娥,梁长虹,赵振军,林华欢,曾辉,何晖,茹光腾.CT肺灌注在肺结节诊断中的应用研究[J].中华放射学杂志,2005,39(10):1041-1045. 被引量:95
  • 3阮超美,陈文静,郑列,莫运仙,周志伟,吕衍春,谢传淼,李立,吴沛宏.CT灌注成像在肺部肿物诊断及鉴别诊断中的应用研究[J].癌症,2007,26(1):78-83. 被引量:13
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