摘要
微电极是脑深部刺激治疗的关键器件。工作时,通过电极上的刺激触点对脑深部作用区域进行电刺激以治疗患者的运动失调症状。文章应用有限元分析软件ANSYS进行微电极对脑深部作用区域刺激过程的计算机仿真,计算和建立刺激触点长度、刺激触点间距等微电极的结构参数与脑部作用区域的刺激强度和刺激范围的关系。结果表明,随着微电极上触点长度和触点间距的增加,脑深部作用区域的刺激强度和刺激范围均有不同程度的增大。分析结果为微电极的改进设计提供了理论依据。
Microelectrode is a key device of deep brain stimulation. The stimulating points attached to the microelectrode can stimulate the deep brain region to treat various neurological disorders. This paper established a finite element model by the microelectrode during deep-brain stimulation in ANSYS environment to investigate size of the stimulating points or the gaps between the contact points, and its influence on the cerebral electric field. The calculation results show that the stimulation intensity and effective range of the activation volume are increased gradually with the growth of the size or gap of the contact points, which can provide theoretical evidence for practical design of microelectrode in deep brain stimulation.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2008年第39期7649-7652,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
基金
中国博士后科学基金资助项目(20070410377)
国家"八六三"计划项目(2006AA04Z370)
西安市应用材料创新基金资助项目(XA-AM-200709)~~
