3Casaburi R,Briggs DD Jr, Donohue JF,et al. The spirometric efficacy of once-daily dosing with tiotropium in stable COPD:a 13-week muhicenter trial. The US tiotropium study group [J]. Chest, 2000 ; 118 : 1294-302.
4Krstic MD, Rogatsky I, Yamamoto KR, et al. Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor. Mol Cell Biol,1997,17(7) :3947.
5Eickelberg O, Roth M, Lorx R, et al. Ligand-independent activation of the glucocorticoid receptor by beta2-adrenergic receptor agonists in primary human lung fibroblasts and vascular smooth muscle cells.Biol Chem J,1999,274(2) :1005.
6Dowling RB, Johnson M, Cole PJ, et al. Effect of flutieasone propiohate and sahneterol on Pseudomonas aeruginosa infection of the respiratory mucosa in vitro. Eur Respir J,1999,14(2) :363.
7Dowling RB,Johnson M,Cole PJ,et al. Effect of salmeterol on Haemophilus influenzae infection of respiratory mucosa in vitro. Eur Respir J,1998,11(1) :86.
8ho K, Lim S, Adcock IM,et al. Effect of low-dose theophyllin on histone deacetylase activity in patients with mild asthma. Am J Respir Crit Care Meal,2000,161 :A614.
9Barnes PJ,Stockley RA.COPD:current therapeutic interventions and future approaches.Eur Respir J,2005,25:1084-1106.
9Osman LM,Ayres JG,Garden C,et al.A randomised trial of home energy efficiency improvement in the homes of elderly COPD patients[J].Eur Respir J,2010,35(2):303-309.
10Young J,Donahue M,Farquhar M,et al.Attitudes to Using Opioids to Treat Dyspnea in Advanced COPD:A Qualitative Study of Family Physicians and Respiratory Therapists[J].Can Fam Physician,2012,58(7):e401-407.
