摘要
【目的】寻找急性肾损伤(acute kidney injury,AKI)早期诊治的相关指标。【方法】对入住儿童重症监护中心(PICU)符合急性肾损伤诊断标准的患儿25例,抽血查血浆IL-1、IL-6、TNF-α与同期入院PICU无急性肾损伤患儿167例以及同期健康体检儿童22例进行对比。【结果】有急性肾损伤患儿组血浆IL-1、IL-6、TNF-α水平比无急性肾损伤患儿组,健康体检儿童组明显升高。【结论】血浆IL-1、IL-6、TNF-α能否作为一个急性肾损伤的生物学指标目前仍处于初级阶段,有待进一步的临床验证。
[Objective] To explore some related parameters of early diagnosis and treatment of acute kidney injury （AKI）. [Methods] Plasma IL-1, IL-6 and TNF-α levels of 25 cases with AKI in pediatric intensive care unit （PICU）, 167 cases with no AKI in PICU and 22 healthy children at the same time were detected and compared. [Results] Compared with the cases without AKI and healthy children, plasma IL-1, IL-6 and TNF-α levels of AKI children increased significantly. [Conclusion]It is still at elementary stage whether the plasma IL-1, IL-6 and TNF-α levels can be served as biological parameters of early diagnosis and treatment for acute kidney injury （AKI） , and clinical verification is needed in the future.
出处
《医学临床研究》
CAS
2008年第10期1785-1786,共2页
Journal of Clinical Research
