摘要
目的观察人工肝支持系统治疗重型肝病、肝衰竭的疗效及影响因素。方法选取我院各种原因引起的急、慢性肝病住院病人,肝脏功能严重损害325例,其中内科综合治疗组107例,人工肝治疗组218例,两组均采用常规方法治疗,而治疗组同时加用人工肝支持疗法。结果人工肝治疗组218例病人,共计进行各种人工肝治疗967例次。治疗后显效90例,好转54例,显效好转率达66.06%,与对照组的显效、好转率33.94%相比有显著性差异。不良反应发生率为8.52%。结论人工肝支持系统是重型肝病、肝衰竭有效的支持疗法,应用人工肝支持系统可显著提高疗效,两组比较有效率有显著性差异。治疗前病人的基础状态、凝血酶原活动度、人工肝方法的组合、人工肝治疗时机的选择等是重要的影响因素。
Objective To observe the clinical efficacy and influencing factors of artificial liver support system （ALSS） in treating fulminant hepatitis and liver failure. Methods 325 patients were selected and divided into two groups as follows ：107 cases for the treatment group,218 cases for the control group. Both of the groups were treated with routine medical program. However, the treatment group was treated with artificial liver support system（ALSS）. Results In the treatment group, 90 effective cases and 54 improved cases were observed. The therapeutic efficiency was 66.06%. The rate of side effect was 8.52%. In the control group, the efficiency was only 33.94%. there was an obvious difference between the two groups. Conclusion ALSS could improve the treatment efficacy of the patients with the fulminant hepatitis and liver failure. The choice on basic state of the patients, PTA, combination of ALSS and curative opportunity before the treatment were important influencing factors.
出处
《透析与人工器官》
2008年第3期1-7,共7页
Chinese Journal of Dialysis and Artificial Organs
关键词
人工肝支持系统
重型肝病
肝衰竭
疗效
影响因素
artificial liver support system（ALSS）
fulminant hepatitis
liver failure
efficacy
influencing factots
