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脂肪细胞促酰化蛋白促进下游信号蛋白的表达 被引量：1

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作者 温宇 王宏伟 胡秀芬 徐辉 吴静 卢慧玲 魏俊
机构地区 华中科技大学同济医学院附属同济医院儿科 湖北省中山医院肾科
出处 《基础医学与临床》 CSCD 北大核心 2008年第10期1095-1096,共2页 Basic and Clinical Medicine
基金 国家自然科学基金(30470645和30600213) 国家自然科学基金对外合作与交流项目(30611120149)
关键词 促酰化蛋白 蛋白激酶C(PKC) 信号蛋白 脂肪细胞 protein 蛋白表达水平 信号途径 信号分子
分类号 R341 [医药卫生—基础医学]
  • 相关文献

参考文献6

  • 1Maslowska M, Wang Hongwei, Cianflone K. Novel roles for acylation stimulating protein/C3adesArg: a review of recent in vitro and in vivo evidence [ J ]. Vitam Horm, 2005, 70 : 309 - 332.
  • 2Maslowska M, Legakis H, Assadi F, et al. Targeting the signaling pathway of acylation stimulating protein [ J ]. J Lipid Res, 2006, 47:643 - 652.
  • 3温宇,王宏伟,卢慧玲,胡秀芬,施虹,杨杨,康闽,王丹丹.脂肪酸诱导的3T3-L1脂肪细胞胰岛素抵抗的研究[J].中国病理生理杂志,2007,23(3):543-547. 被引量：23
  • 4Imamura T, Vollenweider P, Egawa K, et al. Gαq/11 protein plays a key role in insulin induced glucose transport in 3T3-L1 adipocytes [ J ]. Mol Cell Biol, 1999,9 : 6765 - 6774.
  • 5Cabrera-Vera TM, Vanhauwe J, Thomas TO, et al. Insights into G protein structure, function, and regulation [J]. Endocr Rev,2003, 24:765 -781.
  • 6Kanzaki M, Mora S, Hwang JB, et al. Atypical protein kinase C (PKCzeta/lambda) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathways [ J ]. J Cell Biol, 2004,164 : 279 - 290.

二级参考文献7

  • 1卢慧玲,王宏伟,林汉华.促酰化蛋白诱导3T3-F442A前脂肪细胞分化的研究[J].中国病理生理杂志,2005,21(2):243-246. 被引量：4
  • 2Cederberg A,Enerback S.Insulin resistance and type 2 diabetes-an adipocentric view[J].Curr Mol Med,2003,3 (2):107-125.
  • 3Faraj M,Lu HL,Cianflone K.Diabetes,lipids,and adipocyte secretagogues[J].Biochem Cell Biol,2004,82(1):170-190.
  • 4van Epps-Fung M,Williford J,Wells A,et al.Fatty acid-induced insulin resistance in adipocytes[J].Endocrinology,1997,138 (10):4338 -4345.
  • 5Sinha S,Perdomo G,Brown NF,et al.Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B[J].J Biol Chem,2004,279 (40):41294 -41301.
  • 6Lundgren M,Eriksson JW.No in vitro effects of fatty acids on glucose uptake,lipolysis or insulin signaling in rat adipocytes[J].Horm Metab Res,2004,36(4):203-209.
  • 7Chavez JA,Summers SA.Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes[J].Arch Biochem Biophys,2003,419(2):101-109.

共引文献22

同被引文献14

  • 1温宇,王宏伟,卢慧玲,胡秀芬,施虹,杨杨,康闽,王丹丹.脂肪酸诱导的3T3-L1脂肪细胞胰岛素抵抗的研究[J].中国病理生理杂志,2007,23(3):543-547. 被引量：23
  • 2Maslowska M,Wang HW,Cianflone K.Novel roles for acylation stimulating protein/C3adesArg:a review of recent in vitro and in vivo evidence[J].Vitam Horm,2005,70:309-332.
  • 3Wamba PC,Mi J,Zhao XY,et al.Acylation stimulating protein but not complement C3 associates with metabolic syndrome components in Chinese children and adolescents[J].Eur J Endocrinol,2008,159(6):781-790.
  • 4Koutsari C,Jensen MD.Free fatty acid metabolism in human obesity[J].J Lipid Res,2006,47(8):1643-1650.
  • 5Maslowska M,Sniderman AD,Germinario R,et al.ASP stimulates glucose transport in cultured human adipocytes[J].Int J Obes,1997,21(4):261-266.
  • 6Maslowska M,Legakis H,Assadi F,et al.Targeting the signaling pathway of acylation stimulating protein[J].J Lipid Res,2006,47(3):643-652.
  • 7Munzberg H,Myers MG Jr.Molecular and anatomical determinants of central leptin resistance[J].Nat Neurosci,2005,8(5):566-570.
  • 8Mullen KL,Smith AC,Junkin KA,et al.Globular adiponectin resistance develops independently of impaired insulin-stimulated glucose transport in soleus muscle from high-fat fed rats[J].Am J Physiol Endocrinol Metab,2007,293(1):E83-E90.
  • 9Mamura T,Vollenweider P,Egawa K,et al.Gαq/11 protein plays a key role in insulin induced glucose transport in 3T3-L1 adipocytes[J].Mol Cell Biol,1999,19(9):6765-6774.
  • 10Cabrera-Vera TM,Vanhauwe J,Thomas TO,et al.Insights into G protein structure,function,and regulation[J].Endocr Rev,2003,24(6):765-781.

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二级引证文献4

基础医学与临床
2008年 第10期

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