摘要
目的:探讨噬血细胞综合征的实验结果分析。方法:回顾分析16例噬血细胞综合征的实验结果。结果:16例外周血均表现全血细胞减少,9例T细胞亚群分析CD4/CD8比例降低,16例骨髓象主要特点为吞噬有红细胞和(或)粒细胞和(或)血小板的噬血性组织细胞增多,肝酶增高、明显高甘油三脂血症、低纤维蛋白血症、凝血三项PT、TT、APTT均延长,FIB降低。结论:骨髓象找到吞噬了完整形态、数量不等的有核细胞、红细胞或血小板的噬血细胞为噬血细胞综合征诊断依据,CD4/CD8比例降低,噬血细胞综合征患者出现TG升高、SF升高,FIB减低和APTT时间延长,临床上有上述情况,必须警惕HPS发生。
Objectlve：To investigate the experimental result of the hemophagocytic syndrome. Methods：A retrospective analysis of 16 cases of hemophagocytic syndrome was performed. Results：All of 16 cases of hemophagocytic syndrome result showed all of their peripheral blood ceils decreased, nine cases of T - cell subsets of CD4/CD8 ratio decreased. The key characteristics of myelogram of the 16 cases showed the number of Maerophage blood cells that phagocytized the erythrocytes and （or） tablets cells and （or） blood platelet increased, liver enzymes increased, significant hypertriglyceridemia, low fibrin hyperlipidemia, PT, TT, APTT extension, and FIB lower. Condusion： Hemophagocyte phagocylized karyocytes with normal morphology, erythrocytes or platelets is the diagnostic criteria of hemophagocytie syndrome. CD4/CD8 ratio decreased, hemophagocytic syndrome patients appeared the increasing of triglyeeride. Serum ferrtin, activated partial thromboplastin time and decreasing of fibrinogen. When this kind of situation appears, HPS must be vigilant in.
出处
《中国卫生检验杂志》
CAS
2008年第11期2315-2316,2336,共3页
Chinese Journal of Health Laboratory Technology
关键词
噬血细胞综合征
细胞形态
诊断
Hemophagocytic syndrome
Cell morphology
Diagnosis
