摘要
目的探讨急性胰腺炎时凝血功能的变化。方法选择急性胰腺炎患者55例,其中仅有局部表现的患者20例(局部症状组),有全身炎症反应综合征(SIRS)而无器官功能障碍的患者20例(SIRS组),出现器官功能障碍的患者10例(器官功能障碍组),死亡患者5例(死亡组)。择期胆囊切除术术前检查凝血功能正常的同期住院患者10例(对照组)。检测上述患者的血小板计数、凝血酶原时间、活化部分凝血酶时间和纤维蛋白原。结果局部症状组血小板计数、凝血酶原时间、活化部分凝血酶时间和纤维蛋白原与对照组比较差异均无统计学意义;SIRS组、器官功能障碍组和死亡组血小板计数显著低于对照组,凝血酶原时间、活化部分凝血酶时间显著长于对照组,纤维蛋白原显著高于对照组。结论急性胰腺炎发展到SIRS、器官功能障碍和死亡阶段时,凝血功能表现为紊乱状态。
Objective To investigate the changes of blood coagulation function in acute pancreatitis. Methods 55 acute pancreatitis patients were studied, including 20 cases with local manifestation （ local manifestation group） , 20 cases with systemic inflammatory response syndrome （SIRS） and without organ dysfunction （ SIRS group ） , 10 cases with organ dysfunction （ organ dysfunction group ） , 5 cases died （died group）, 10 cases of selective cholecystectomy patients were studied （control group）. Platelet count, prothrombin time, activated partial thromboplastin time and fibrinogen were analyzed in all the patients. Results No significant differences in blood coagulation function was found between control group and local manifestation group. In SIRS group, organ dysfunction group and died group, platelet count was significantly lower than that in control group, prothrombin time and activated partial thromboplastin time were significantly longer than those in control group, fibrinogen was significantly higher than that in control group. Conclusion Blood coagulation function disorder occurred when acute pancreatitis patients have SIRS, organ dysfunction or died.
出处
《中国急救医学》
CAS
CSCD
北大核心
2008年第11期984-986,共3页
Chinese Journal of Critical Care Medicine
关键词
急性胰腺炎
凝血功能
紊乱
Acute pancreatitis
Coagulation function
Disorder
