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富马酸喹硫平与奋乃静治疗精神分裂症对照研究 被引量:3

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摘要 目的:比较富马酸喹硫平与奋乃静对精神分裂症的疗效及不良反应。方法:60例精神分裂症患者随机分为两组,分别给予富马酸喹硫平与奋乃静治疗,疗程8周。以阳性与阴性症状量表(PANSS)评定疗效,副反应量表(TESS)评定不良反应。结果:富马酸喹硫平和奋乃静之间疗效差异无显著性(P>0.05),富马酸喹硫平组的不良反应发生率低于奋乃静组,差异有显著性(P<0.05)。结论:富马酸喹硫平组与奋乃静对治疗精神分裂症的疗效相当,有效率分别为86%、83%。富马酸喹硫平锥体外系不良反应明显少于奋乃静,尤其是对女性精神分裂症患者内分泌影响较小,更适于女性精神分裂症患者。
出处 《中国民康医学》 2008年第23期2786-2787,共2页 Medical Journal of Chinese People’s Health
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