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外伤性脑积水脑脊液蛋白质含量的临床意义 被引量:4

Clinical Significance of Cerebrospinal Fluid Protein Content in Patients with Traumatic Hydrocephaly
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摘要 目的探讨外伤性脑积水手术适应症。方法对比分析38例外伤性脑积水患者腰大池与脑室内脑脊液蛋白质含量、压力、细胞数及氯化物的不同。结果38例外伤性脑积水的病人腰大池与脑室内脑脊液压力、白细胞数及氯化物含量差异无统计学意义,而脑脊液蛋白质含量的差异具有显著意义。12例腰大池及脑室内蛋白质含量均大于0.5g/L者,堵管发生4例,22例腰大池内脑脊液蛋白质含量大于0.5g/L,而脑室内蛋白质含量均小于0.5g/L者,堵管发生1例。4例腰大池及脑室内蛋白质含量均小于0.5g/L者,未发生堵管。结论外伤性脑积水患者腰大池与脑室内脑脊液蛋白质含量的差异有统计学意义。单纯腰大池内脑脊液蛋白质含量高于0.5g/L者并不是脑室腹腔分流术的禁忌症。 Objective To investigate the operative indications of traumatic hydrocephaly. Methods The protein content,pressure, cell counting and chloride of cerebrospinal fluid(CSF) in lumber cistern and brain ventricle were detected and compared in 38 traumatic patients with hydrocephaly. Results In all 38 cases, there was statistical difference in protein content, but not in pressure,leukocyte and chloride, of CSF between lumber cistern and brain ventricle. The rate of shunt ductus blocking up was 33 % (4/12) in cases with protein content of CSF exceeding 0. 5 g/L in both lumber cistern and cerebral ventricle ,4.5 % ( 1/22 ) in cases with protein content of CSF exceeding 0.5 g/L only in lumber cistern, and 0 (0/4) case with protein content of CSF less than 0.5 g/L both in lumber cistern and in cerebral ventricle. Conclusions There is statistical difference in protein content of CSF between lumber cistern and brain ventricle in traumatic patients with hydrocephaly. The protein content of CSF exceeding 0.5 g/L only in lumber cistern is not the contraindication to ventriculoperitoneal shunt operations.
出处 《中华全科医学》 2008年第12期1237-1238,共2页 Chinese Journal of General Practice
关键词 外伤性 脑积水 腰大池 脑室 脑脊液 蛋白质 Traumatic hydrocephaly Lumber cistern Ventricle of brain Cerebrospinal fluid Protein
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