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TAC1在白念珠菌对抗真菌药物产生耐药性中的作用 被引量:1

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摘要 由于器官移植患者大量使用免疫抑制剂、癌症患者长期接受放化疗以及广谱抗生素的滥用和艾滋病的广泛传播,免疫功能低下者人数不断增多,真菌感染发生率逐年增加,尤其是白念珠菌(Candida albicans)感染最为常见。三唑类药物氟康唑是治疗念珠菌感染的常用药物,长期用药和重复给药往往会引起耐药现象,最终导致治疗失败。目前已经明确的白念珠菌的耐药机制主要包括:
出处 《中国医药生物技术》 CSCD 2008年第6期451-453,共3页 Chinese Medicinal Biotechnology
基金 国家自然科学基金(30500027)
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