摘要
以植物生长调节剂2,4-二氯苯氧乙酸(2,4-D)为囊芯,以液体石蜡为连续油相,Span-80为乳化剂,戊二醛为交联剂,在W/O型乳化体系中,采用乳化-交联方法成功制备了2,4-D-明胶/壳聚糖/葡甘聚糖复合微球。并考察了明胶、壳聚糖和葡甘聚糖三者的质量比,交联剂戊二醛的用量,乳化剂Span-80的用量,油水比,乳化时间,固化时间等因素对微球的大小和形貌的影响,芯壁材比对包封率的影响。结果表明:当明胶、壳聚糖和葡甘聚糖三者的质量比为1∶1∶1,戊二醛的用量为10 mL,Span-80为2 mL,油水比为1.5∶1,乳化30 min时,制备出的微球形态圆整,表面光滑,球粒适中并有良好的分散性。芯壁材之比为1∶20时,其包封率可达78.3%,且具有良好的缓释性能。该复合微球可望在农业领域得到应用。
With 2, 4-Dichlorophenoxyacetic Acid as matrix materials, liquid paraffin as continuous phase, Span-80 as emulsifier, glutaradehyde as crosslinking agent, the 2,4-D-gelatin-chitosankonjae glucomannan microspheres were Produced by an emulsion-crosslinking method, in the W/ O emulsion system. And several reaction parameters were investigated in detail, including the ratio gelatin, chitosan and konjac glucomannan, the dosage of glutaradehyde and Span-80, the ratio of oil to water, emulsifying time, curing time, the speed and the size as well as the appearance of the mierospheres, and the ration between core and wall materials on the encapsulation efficiency. The results show when the mass ratio of gelatin, chitosan, konjac glucomannan equals to 1 ： 1 ： 1, the dosage of glutaradehyde is 10 mL, the mass ratio oil to water is equal to 1.5 ： 1, emulating time is 30 min, microspheres formed with smooth surface, reasonable size and better dispersivity. When the ration between core and wall materials is 1 ： 20, the encapsulation efficiency attained to 78.3% and produced a good slow release property. The microspheres could be applied in agricultural development.
出处
《皮革科学与工程》
CAS
2008年第6期27-31,共5页
Leather Science and Engineering
基金
四川省教育厅重点项目(编号2006A129)
关键词
明胶
壳聚糖
葡甘聚糖
2
4-二氯苯氧乙酸
复合微球
缓释性能
gelatin
chitosan
konjac glucomannan
2, 4-Dichlorophenoxyacetic Acid （2, 4-D）
microspheres, slow release property
