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胃肠道间质瘤的诊断与治疗 被引量:2

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摘要 胃肠道间质瘤(gastrointestinal stromal tumors,GIST)是消化道最常见的间叶组织来源的肿瘤,有别于胃肠道肌源性或神经源性的肉瘤。1983年Mazur等首先提出GIST这一概念,10年前Hirota等发现了其分子特征。目前GIST被定义为组织学上富于梭形细胞、上皮样细胞,偶或多形性细胞,呈束状、弥漫状排列,免疫表型上表达KIT蛋白(CD117)、巢蛋白(nestin)以及功能未知蛋白(discovered on GIST1,DOG1),
出处 《医学新知》 CAS 2008年第6期315-319,324,共6页 New Medicine
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