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脑梗死患者血糖和糖化血红蛋白与纤溶酶原激活物抑制物1的相关性研究

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摘要 目的探讨血浆纤溶酶原激活物抑制物1（PAI-1）活性与急性脑梗死患者空腹血糖（FPG）及糖化血红蛋白（HbAIC）的关系。方法应用酶联免疫吸附双抗体夹心法检测急性脑梗死患者（162例）血浆PAI-1活性。结果（1）血脂、体重指数、C-反应蛋白（CRP）、神经功能评分与PAI-1活性无明显相关（P〉0．05）。（2）急性脑梗死患者FPG、HbAlc与PAI-1活性密切相关（R=0．177，0．179，P〈0．05）。结论FPG、HbAlc与PAI-1活性升高有关，积极控制FPG、HbAlc可能降低PAI-1活性，改善预后。
作者 朱凌云 孙侃 李晓军
机构地区 新疆石河子大学第一附属医院内分泌科 新疆石河子大学第一附属医院神经内科
出处 《中国医师杂志》 CAS 2008年第11期1545-1546,共2页 Journal of Chinese Physician
关键词 脑梗塞 血糖 血红蛋白A 糖基化 纤溶酶原激活物抑制物1
分类号 R743.33 [医药卫生—神经病学与精神病学]
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参考文献11

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二级参考文献44

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中国医师杂志
2008年 第11期

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