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降钙素原和慢性阻塞性肺疾病急性加重期抗生素治疗 被引量：1

Procalcitonin and strategy of antibacterial treatment in acute exacerbation of chronic obstructive pulmonary disease
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摘要 慢性阻塞性肺疾病急性加重期（acute exacerbation of chronic obstructive pulmonary diseases，AECOPD）抗生素治疗仍存争议。最新研究表明在AECOPD中，动态监测降钙素原（procalcitonin，PCT）水平对抗生素的应用有明确的指导作用，可以减少不必要的抗生素应用，缩短应用时间，防止耐药。PCT指导策略在被建议成为全球AECOPD抗生素治疗方案之前，尚面临几个关键问题有待解决。 The role of antimicrobial in acute exacerbation of chronic obstructive pulmonary diseases （AECOPD） remains controversial. Recent reports have shown that the dynamic determination for procaleitonin（PCT） could instruct antibiotic use,decrease unnecessary exposure time, shorten the course of treatment,and prevent antibiotic resistance in AECOPD. But, some important questions remain before PCT guided therapy can be recommended as a worldwide standard approach to AECOPD antimierobial management.
作者 王岚 蔡柏蔷
机构地区 中国协和医科大学北京协和医院呼吸科
出处 《国际呼吸杂志》 2008年第23期1460-1463,共4页 International Journal of Respiration
关键词 降钙素原 慢性阻塞性肺疾病急性加重期 抗生素治疗 Procalcitonin Acute exacerbation of chronic obstructive pulmonary diseases Antimicrobial
分类号 R563 [医药卫生—呼吸系统] R563.1 [医药卫生—呼吸系统]
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参考文献28

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二级参考文献19

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国际呼吸杂志
2008年 第23期

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