摘要
目的研究超声辅助提取紫金砂中总香豆素的最佳提取工艺。方法以总香豆素提取率为指标,考察超声提取温度、提取功率、提取时间、料液比、提取次数对紫金砂总香豆素提取的影响。选用正交试验设计法对紫金砂的超声辅助提取工艺进行优选。结果超声辅助提取紫金砂中总香豆素的最佳工艺为:65℃,超声功率90 W,以1∶18的料液比加入丙酮,超声提取50 min,提取4次。结论通过验证实验,表明所选的工艺条件可行,在该工艺条件下每克紫金砂平均可提取总香豆素27.4 mg。
OBJECTIVE To optimize ultra sonic-assisted extraction process of total coumarins from Angelica polymorpha Maxim. METHODS The extraction rate of total coumarins was used as index and the experimental conditions were investigated, such as solvent, extraction temperature, extration power, extration time, the ratio of solid to liquid and extraction times. The optimal extraction condition was obtained by orthogonal test. RESULTS Optimum technological conditions were determined as follows： 65 ℃, 90 W,50 min, the ratio of solid to liquid was 1： 18, ultra sonic-assisted extracting for four times. CONCLUSION The process is feasible and useful for extracting total eoumarins from Angelica polymorpha Maxim. , with average extraction rate of total eoumarins as 27.4 mg·g^-1.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2009年第1期26-29,共4页
Chinese Journal of Modern Applied Pharmacy
基金
湖北省教育厅自然科学研究项目(20081302)
天然产物开发与利用湖北省重点实验室开放基金资助项目(2006NP08)
关键词
紫金砂
总香豆素
超声辅助提取
正交试验
Angelica polymorpha Maxim.
total coumarins
ultra sonic-assisted extraction
orthogonal test
