摘要
目的探讨慢性阻塞性肺疾病(COPD)稳定期中医不同证型与血清瘦素水平的关系及其意义。方法采用放射免疫法测定60例稳定期COPD患者血清瘦素水平,中医证型分别为脾肺肾气虚、肺肾阴虚及脾肾阳虚,并进行统计学分析。结果COPD稳定期中医各证型血清瘦素水平不同,其中以肺脾肾气虚型最高,脾肾阳虚型最低,肺肾阴虚型居中。三组之间瘦素水平比较均有显著差异。结论COPD稳定期从气虚、阴虚到阳虚患者机体炎症反应逐渐加重,营养状况逐渐恶化,提示其预后及转归有差异。
Objective： To explore the relationship between serum leptin level and syndrome of TCM of patients with chronic obstructive pulmonary disease（COPD）in stable phase. Methods：A total of sixty patients with COPD in stable phase were randomly divided into three groups ： Deficiency of Qi of lung - spleen - kidney group, Deficiency of Yin of lung - kidney group and Deficiency of Yang of spleen - kidney group, and serum leptin level was measured by using radioimumoassay. The relationship between serum leptin level and syndrome of TCM were analyzed. Results： The serum leptin levels of the patients in the three groups from low to hight were Deficiency of Yang of spleen - kidney group, Deficiency of Yin of lung - kidney group and Deficiency of Qi of lung - spleen - kidney group, there were significantly difference among three groups. Conclusion：The serum leptin levels are singnificantly difference in differential syndrome of TCM in patients with chronic obstructive pulonary disease in stable phase.
出处
《中国中医急症》
2009年第2期229-230,265,共3页
Journal of Emergency in Traditional Chinese Medicine
基金
广东省中医药局建设中医强省科研课题(No.2060118)
关键词
慢性阻塞性肺疾病
中医证型
瘦素
Chronic obstructive pulmonary diseases
Syndrome of TCM
Leptin
