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早期肠内营养对脑卒中病人营养状态和预后的影响 被引量:10

Effect of early enteral nutrition on nutritional status and prognosis in patients with acute stroke
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摘要 目的:评估EEN对脑卒中病人营养状态和预后的影响。方法:将48例脑卒中病人随机分为EEN组和延迟EN(DEN)组。EEN组于患病72 h内开始给予EN支持;DEN组患病72 h后、6 d内开始给予EN支持。入院第1和第14天检测两组病人的营养指标和NIHSS评分,第14天观察感染性并发症,第30天对住院病人和已出院的病人进行Rankin修订量表评分。结果:入院时,两组的营养指标和NIHSS评分均无显著性差异。入院后14d,EEN组血清ALB和PA显著高于DEN组(P<0.05);两组病人NIHSS评分较入院时均有改善,EEN组优于DEN组;EEN组病人的感染发生率明显少于DEN组(P<0.05)。入院第30天,EEN组病人的Rankin修订量表优于DEN组(P<0.05)。结论:对伴有进食障碍的脑卒中病人,EEN支持能稳定营养状态,减少感染性并发症,促进神经功能恢复,提高生活质量,改善预后。 Objective : To investigate the effects of early enteral nutrition on nutritional status and prognosis in patients with acute stroke. Methods: 48 cases of acute stroke were divided into early enteral nutrition group (EEN) and delayed enteral nutrition group(DEN) randomly. EEN group received enteral nutrition diet within 72h from onset and DEN groul; teceived enteral nutrition diet after 72 h but within 6 days from onset. The levels of nutritional parameters and National Institution of Health Stroke Scale( NIHSS) were assessed at the 1st day and the 14th day after admission. The rates of infective complications were observed at the 14th day after admission and the revised Rankin scale was assessed at the 30th day after admission. Results: The nutritional parameters and NIHSS had no difference at admission. Albumin and prealbumin were significantly higher in the EEN group than those in DEN group at the 14th day after admission (P 〈 0.05 ). NIHSS was improved at the 14th day in two groups and better in EEN group (P 〈 0.05). The rates of infection complications in the DEN group were obviously higher more than in EEN group at the 14th day after admission (P 〈 0.05). At the 30th day, the revised Rankin scale of EEN group was significantly lower than that of the DEN group ( P 〈0. 05 ). Conclusion : Early enteral nutrition support can significantly improve nutritional status, decrease the incidence of infective eomplications and improve the clinical prognosis in patients with acute stroke.
作者 王琳 徐运
出处 《肠外与肠内营养》 CAS 北大核心 2009年第1期23-25,28,共4页 Parenteral & Enteral Nutrition
关键词 肠内营养 脑卒中 营养状态 Enteral nutrition Stroke Nutrition status
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