摘要
目的调查县级医院尿路感染病原菌的分布情况及耐药性,为临床医师合理使用抗菌药物提供科学依据。方法对医院2003-2007年336株尿路感染病原菌用常规方法进行鉴定,用纸片扩散法(K-B法)进行药物敏感性监测。结果革兰阴性杆菌分离率为78.3%,革兰阳性球菌分离率为16.4%;大肠埃希菌分离率最高,占64.9%;除革兰阳性球菌对万古霉素100%敏感、革兰阴性杆菌对亚胺培南100.0%敏感外,所有病原菌对其他多种抗菌药物产生了不同程度的耐药性;大肠埃希菌和肺炎克雷伯菌中产超广谱β-内酰胺酶(ESBLs)检出率分别为25.7%和28.0%。结论医院尿路感染病原菌已产生了一定的耐药性,应采取有效措施进行预防与控制。
Abstract： OBJECTIVE To investigate distribution status and drug-resistance of pathogens from infected urinary tract and offer scientific evidence for reasonably clinical usage of antibiotics. METHODS A total of 336 strains of pathogenic bacteria isolated from urinary tract infection from 2003 to 2007 were identified, and antibiotic susceptibility test was performed by K-B methods. RESULTS The total isolating rate of Gram-negative bacilli was 78.3%. And that of Gram-positive cocci was 16.40%. Escherichia coli accounted for 64.9%, ranking the first, Except for 100% sensitive to vancomycin in Gram positive cocci and 100 %0 sensitive to imipenem in Gram-negative bacilli, all pathogens were resistant to the other antibiotics in different degrees. The detection rate of extensive- spectrum beta-lactamases （ESBLs） producers in E. coli and Klebsielga pneumoniae were 25. 7% and 28.0%, respectively. CONCLUSIONS The drug-resistance of pathogenic bacteria from infected urinary tract emergs in Yinshan County. We should adopt effective measurement to prevent and control it.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第1期102-104,共3页
Chinese Journal of Nosocomiology
关键词
县级医院
尿路感染
病原菌
耐药性
County hospital
Urinary tract infection
Pathogens
Drug-resistance
