摘要
目的探讨个体化方案治疗高危良性前列腺增生症的临床效果及安全性。方法对87例高危良性前列腺增生症患者进行个体化围手术期处理,采用标准经尿道前列腺切除术(TURP)(22例)、低容量大通道TURP(37例)和低容量小通道TURP(28例)手术治疗,观察手术治疗效果及安全性。结果全部病例均顺利耐受手术,无严重并发症,无输血病例。标准TURP组、低容量大通道TURP组和低容量小通道TURP组平均手术时间分别为(65.5±2 1.2)、(32.4±17.5)和(16.5±3.6)min;术中平均失血量分别为(148.4±45.3)、(84.7±37.2)和(32.4±1 5.7)ml;平均切除组织量分别为(41.2±10.5)、(25.4±6.3)和(11.3±3.2)g。后两种方法与标准TURP组相比,差异有统计学意义(P<0.05)。所有病例随访3～28个月,国际前列腺症状评分(IPSS评分)分别降低(19.7±6.8)、(17.9±6.4)和(15.7±9.5)分;最大尿流率分别增加(13.4±8.4)、(12.7±9.4)和(11.4±5.4)ml/s;生活质量评分(QOL)分别下降(2.2±0.2)、(2.1±0.2)和(2.4±0.4)分;剩余尿量(RUV)分别下降(135.7±68.4)、(158.8±87.5)、(147.6±65.7)ml。组间疗效比较差异无统计学意义(P>0.05)。结论个体化围手术期治疗和个体化TURP是治疗高危BPH的安全有效方法,值得推广。
To evaluate the clinical efficacy and safety of individual treatment for high risk BPH patients. Methods Under the individual treatment during perioperative period, 87 high risk BPH patients received standard TURP（Group 1, n=22）, low-volume large passage TURP（Group 2, n=37） or low-volume small passage TURP（Group 3, n=28） respectively. The clinical efficacy and safety of treatments were evaluated. Results All patients were tolerable for the operations without serious complications and blood transfusion. In group 1,2 and 3, the mean operation time was（65.5±21.2）, （32.4±17.5） and （16.5±3.6）min; the mean volume of blood loss in the period of operation was （148.4±45.3）, （84.7±37.2） and （32.4±15.7）ml; the mean weight of resected tissue was （41.2±10. 5）, （25.4±6.3） and （11.3±3.2）g. There were significant differences in above indexs between group 2/3, and group l（P〈0.05）. All patients were followed up from 3 to 28 months, score of IPSS decreased （19.7±6.8）, （17.9±6.4） and （15.7±9.5）; Qmax increased （13.4±8.4）,（12.7±9.4） and （11.4±5.4）m1/s; QOL decreased （2.2±0.2）, （2.1±0.2） and （2.4±0.4）; RUV decreased （135.7±68.4）, （158.8±87.5） and （147.6±65.7）ml respectively. There was no difference in clinical efficacy among three groups （P〉0.05）. Conclusion The individual perioperative treatment and the individual TURP was effective and safe method for treatment of high risk BPH patients.
出处
《中国男科学杂志》
CAS
CSCD
2009年第1期45-47,共3页
Chinese Journal of Andrology
关键词
前列腺增生
经尿道前列腺切除术
prostatic hyperplasia
transurethral resection of prostate
