期刊文献+

小型猪与小鼠腮腺、泪腺、垂体超微结构的观察与比较

Comparative ultrastructural study of parotid gland, lacrimal gland and pituitary gland between miniature pig and mouse
原文传递
导出
摘要 目的研究小型猪及小鼠腮腺的超微结构特点,并将腮腺与泪腺、垂体的超微结构对比观察,旨为涎腺基因治疗转基因表达的生物学特性提供腺体形态学的依据。方法选用成年小型猪、昆明种小鼠各5只,分别取腮腺、泪腺、垂体进行超微结构观察。结果小型猪较小鼠的腮腺腺泡细胞内分泌颗粒密度大,质地均匀,细胞器少见,血管内皮细胞内有较多分泌颗粒存在。小型猪与小鼠泪腺超微结构均与各自腮腺相似,小型猪与小鼠垂体结构特点为细胞排列散在,细胞闻充满血窦及毛细血管。结论小型猪腮腺腺泡细胞分泌颗粒多,其毛细血管内皮细胞中也可见较多分泌颗粒,提示这些分泌颗粒可能进入血液发挥内分泌功能。 Objective To study the ultrastructure of parotid glands, lacrimal glands and pituitary glands between miniature pig and mouse. Methods Five adult miniature pigs and 5 mice were studied. Uhrastructure of their parotid glands, lacrimal glands and pituitary glands was observed. Results The secretary granules in acinar cell of miniature pig parotid glands showed higher density and more aequalis than those of mice. The cell apparatus in acinar cell of mouse parotid glands were more plentiful than those of miniature pigs. The secretary granules on blood vessel wall were richer in parotid gland of miniature pigs compared with mouse parotid gland. Lacrimal gland had the similar ultrastructure to parotid gland in these two animals. Many blood vessel antrums were found in pituitary glands of these two animals. Conclusions Compared with mouse parotid glands, there are more secretary granules in acinar cells and vascular endothelial cells in miniature pig parotid glands, which might enter blood stream and have function of endocrine secretion.
出处 《中华口腔医学杂志》 CAS CSCD 北大核心 2009年第2期108-112,共5页 Chinese Journal of Stomatology
基金 国家自然科学基金(30430690)
关键词 腮腺 泪器 垂体 组织学 比较 Parotid gland Lacrimal apparatus Pituitary gland Histology,comparative
  • 相关文献

参考文献20

  • 1Shackleford JM, Wilborn WH. Structural and histochemical diversity in mammalian salivary glands. Ala J Med Sei, 1968, 5 (2) :180-203.
  • 2何志秀,马文波,卢勇,刘吉余,雷文涛.人和常用实验动物正常涎腺的定量组织学研究[J].华西医科大学学报,1999,30(4):414-416. 被引量:3
  • 3Wang SL, Li J, Zhu XZ, et al. Sialographic characterization of the normal parotid gland of the miniature pig. Dentomaxillofac Radiol , 1998, 27 (3) : 178-181.
  • 4张,王松灵,李钧,董凤英,张春梅,单兆臣.5种哺乳动物涎腺造影及解剖比较研究[J].北京口腔医学,2003,11(4):195-199. 被引量:8
  • 5Leeson CR. The fine structure of the parotid gland of the spider monkey ( Ateles paniscus). Acta Anat ( Basel), 1969, 72 ( 1 ) : 133-147.
  • 6张昕 王松灵 李钧 等.5种哺乳动物涎腺组织学及超微结构观察[J].现代口腔医学杂志,2003,11(4):195-199.
  • 7Li J, Shah Z, Ou G, et al. Structural and functional characteristics of irradiation damage to parotid glands in the miniature pig. Int J Racliat Oncol Biol Phys, 2005,62(5) :1510- 1516.
  • 8Friedrich RE,Bartel-Friedrich S, Holzhausen HJ,et al. The effect of external fraetionated irradiation on the distribution pattern of extracellular matrix proteins in submandibular salivary glands of the rat. J Craniomaxillofac Surg, 2002, 30(4) : 246-254.
  • 9Voutetakis A, Bossis I, Kok MR, et al. Salivary glands as a potential gene transfer target for gene therapeutics of some monogenetic endocrine disorders. J Endocrinol, 2005, 185 : ( 3 ) 363 -372.
  • 10Yan X, Voutetakis A, Zheng CY, et al. Sorting of transgenic secretory proteins in miniature pig parotid glands following adenoviral-mediated gene transfer. J Gene Med, 2007, 9 ( 9 ) : 779-787.

二级参考文献8

共引文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部