摘要
趋化因子CXCL12及其受体CXCR4不仅表达于免疫细胞，在某些肿瘤细胞中也呈高表达。最近研究表明，其与食管癌、胃癌、结直肠癌等的转移密切相关。展开其生物学特性、在消化道肿瘤中的表达及转移相关性研究，将为消化道肿瘤转移的防治提供新的思路。
Chemokine CXCL12 and chemokine receptor CXCR4 express not only in immunocytes, but also in some tumor cells. Recent researches have indicated that their close relationship with metastasis of diges- tive tumors, such as esophageal carcinoma, gastric carcinoma and colorectal carcinoma. Bionomies, expression in digestive tumors, metastatic correlation of CXCLI 2 and CXCR4 are being studied in order to offer a new way of prevention and treatment for metastasis of digestive tumors.
出处
《国际肿瘤学杂志》
CAS
2009年第2期136-138,共3页
Journal of International Oncology
关键词
趋化因子类
受体
趋化因子
消化系统肿瘤
肿瘤转移
Chemotactic factors
Receptors, chemokine
Digestive system neoplasms
Neoplasm metastasis
