摘要
目的了解医院药品不良反应情况,促进医院药品不良反应(ADR)监测报告工作的开展。方法对内江市二医院2007年收集到的227例ADR报告进行统计分析。结果涉及ADR的药物94种,其中抗感染药物引起的ADR占总例数的47.6%(108例),中药制剂占9.2%(21例),抗肿瘤类药物占8.8%(20例);静脉途径给药引起ADR 201例,占88.5%;ADR涉及的器官或系统主要为消化和皮肤及其附件;头孢菌素类发生ADR的29例,占抗感染药物总例数的26.8%;其次是喹诺酮类26例,占24.1%。结论抗感染药引起ADR占比例最多,静脉途径给药是引起ADR的主要途径,应引起重视。
Objective To facilitate the monitoring and reporting of adverse drug reaction （ADR）. Method A total of 227 ADR case raports collected in 2007 were analyzed statistically. Results The drugs that induced ADR totaled 94 kinds. Of the 227 ADR cases, 47.6% （ 108 cases） were induced by anti-infective drugs, followed by traditional Chinese medicinal materials preparations（9. 2%, 21 cases） and ＂antitumor drugs（8.8%, 20 cases）. 201 cases （88.5%）were induced by intravenous injection. Lesions of digestive system, skin and its appendages were the chief clinical manifestations of the ADR. Twenty nine ADR cases induced by cephalosporins and 26 cases by qinolones occupied the first and second constifuent rate （26. 8% and 24. 1% ） of cased induced by anti-infection drugs. Conclusion In order to reduce and aviod the occurrence of ADR, clinical departments should pay great attention to the monitoring and reporting of ADR.
出处
《职业卫生与病伤》
2009年第1期22-24,共3页
Occupational Health and Damage
关键词
药品不良反应
报告
分析
Adverse drug reaction （ADR）
Report
Analysis
