摘要
目的调查自住院患者分离的鲍氏不动杆菌(ABA)的耐药性及其同源性,为临床治疗及预防提供依据。方法110株鲍氏不动杆菌的鉴定和药敏试验采用VITEK2-compact全自动微生物系统,采用REP-PCR进行同源性分析。结果110株菌株表现出多药耐药,仅对阿米卡星敏感率高,为91.3%,对头孢他啶、环丙沙星、亚胺培南等抗菌药物均显示出高水平耐药,分别为100.00%、97.83%、91.30%;REP-PCR提示部分菌株表现出100.00%同源。结论调查的鲍氏不动杆菌为多药耐药株(MDR-ABA),同一克隆株可在不同患者之间传播。
OBJECTIVE To investigate the resistance and the homology of the Acinetobacter baumannii （ABA） strains isolated from inpatients to offer basis for clinical treatment and preservation. METHODS VITEK2-compact system was used to identify 110 ABA strains, and detect their susceptibility to antibiotics. REP-PCR was carried out to detect their homology. RESULTS The 110 isolated strains were multidrug resistant. Rate of sensitivity to amikacin was 91.3%, Rates of resistance to ceftazadime, ciprofloxacin and imipenem were 100.00%, 97.83% and 91.30%, respectively. REP-PCR was confirmed part of them was from the same clone. CONCLUSIONS Most of the isolated strains are multidrug-resistant. The same clone of MDR-ABA probably leads to transmission among patients.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第6期611-613,共3页
Chinese Journal of Nosocomiology
关键词
鲍氏不动杆菌
同源性
耐药
Acinetobacter baumannii
Homology
Drug resistance
