摘要
目的研究中药磨盘草的化学成分。方法运用硅胶柱色谱及Sephadex LH-20柱色谱等方法分离磨盘草的化学成分,通过理化常数和1D-NMR等波谱数据鉴定化合物的结构。结果从磨盘草中分离了7个化合物,鉴定了6个化合物,分别鉴定为:β-谷甾醇(β-sitosterol,1)、齐墩果酸(oleanicacid,2)、24R-5α豆甾烷-3,6-二酮((24R)-5α-stigmastane-3,6-dione,3)、胡萝卜苷(daucosterol,4)、2,6-二甲氧基对苯醌(2,6-dimethoxy-1,4-benzoquinone,5)、香草酸(vanillic acid,6),还有一个脂肪酸类成分。结论化合物2-5均为首次从磨盘草中分得。
Objective To investigate the chemical constituents of Abutilon indicum（ L. ）Sweet. Methods The compounds were isolated by the combined use of column chromatography with silica gel and Sephadex LH- 20. The structures of the compounds obtained were elucidated by physicochemical constants and spectroscop- ic methods. Results Seven compounds were isolated, and six of them were identified as β-sitosterol （ 1 ）, oleanic acid （2）, （ 24R ） -5α-stigmastane-3,6-dione （ 3 ）, daucosterol （ 4 ）, 2,6-dimethoxy-1,4-benzoquinone （5）, vanillic acid （ 6 ）. Conclusions Compounds 2- 5 were obtained from Abutilon indicum （ L. ） Sweet for the first time.
出处
《沈阳药科大学学报》
CAS
CSCD
北大核心
2009年第3期196-197,221,共3页
Journal of Shenyang Pharmaceutical University
关键词
磨盘草
化学成分
锦葵科
Abutilon indicum（ L. ） Sweet
chemical constituents
Malvaceae
