摘要
为探讨支气管哮喘（ＢＡ）患者与ＩＬ－５、ＩＬ－１０含量变化关系及意义，采用定量ＥＬＩＳＡ法检测３８例ＢＡ患者及１５例正常人血清ＩＬ－５、ＩＬ－１０含量。结果：与正常对照组比较，ＢＡ患者ＩＬ－５含量急性期、缓解期均明显升高（Ｐ＜０．０５）；ＩＬ－１０含量急性期明显降低（Ｐ＜０．０１），缓解期升至正常水平（Ｐ＞０．０５）。表明：血清ＩＬ－５、ＩＬ－１０含量变化与ＢＡ患者病情密切相关。
To study the relationship between the variety of serum IL5 and IL10 and the patients condition with bronchial asthma (BA),we detected serum levels of IL5 and IL10 in 38 patients with BA and 15 healthy controls with quantitative ELISA. We found that IL5 elevated significantly in acute and remittent patients (P<0.05). On the other hand, IL10 decreased in acute patients (P<0.01) and then rose to normal levels in remission. These results suggest that the variety of serum IL5 and IL10 relate to the condition of BA patients and dynamic detection may provide a value index for clinal observation.
出处
《免疫学杂志》
CAS
CSCD
北大核心
1998年第2期109-110,共2页
Immunological Journal
