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Th17/Treg平衡在肝纤维化中的作用 被引量:6

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摘要 肝纤维化是慢性肝病发展过程的一个阶段,轻度可以逆转,但当不可逆转时,其转化为肝硬化的概率明显上升。因此,探索肝纤维化的发生机制,在早期控制甚至逆转肝纤维化具有十分重要的临床意义。辅助性T细胞17(T helper cells 17,Th17)和调节性T细胞(regulatory T cells,
出处 《中华临床医师杂志(电子版)》 CAS 2012年第24期8243-8244,共2页 Chinese Journal of Clinicians(Electronic Edition)
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参考文献3

  • 1Li J,Qiu SJ,She WM,et al.Significance of the Balance between Regu-latory T(Treg)and T Helper17 (Th17)Cells during Hepatitis B Virus Related Liver Fibrosis. PLoS One . 2012
  • 2Zhang JY,Zou ZS,Huang A,et al.Hyper-activated pro-inflammatory CD16+monocytes correlate with the severity of liver injury and fibrosis in patients with chronic hepatitis B. PLoS ONE . 2011
  • 3崔瑶,秦明照.Th17细胞生物学功能及与心血管疾病关系的研究进展[J].中华临床医师杂志(电子版),2011,5(8):2357-2359. 被引量:2

二级参考文献28

  • 1程翔,廖玉华,郑金娥,夏春燕,王朝晖,周子华,张家明,陈健,舒砚文,毛小波,袁璟.慢性心力衰竭患者CD4+CD25+调节性T细胞检测及意义[J].临床心血管病杂志,2006,22(3):145-147. 被引量:16
  • 2Hashmi S,Zeng QT.Role of interleukin-17and interleukin-induced cytokines interleukin-6and interleukin-8in unstable coronary arterydisease. Coronary Artery Disease . 2006
  • 3Veldhoen M,Stockinger B.TGFbeta1,a"Jack of all trades":the link with pro-inflammatory IL-17-producing T cells. Trends in Immunology . 2006
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  • 7Li N,Bian H,Zhang J,et al.The Th17/Treg imbalance exists in patients with heart failure with normal ejection fraction and heart failure with reduced ejection fraction. Clinica Chimica Acta . 2010
  • 8Hashmi S,Zeng QT.Role of interleukin-17and interleukin-17-induced cytokines interleukin-6and interleukin-8in unstable coronary artery disease. Coronary Artery Disease . 2006
  • 9McGeachy MJ,Bak-Jensen KS,Chen Y,Tato CM,Blumenschein W,McClanahan T,Cua DJ.TGF-beta and IL-6drive the production of IL-17and IL-10by T cells and restrain T(H)-17cell-mediated pathol-ogy. Nature Immunology . 2007
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