摘要
目的 了解系统性红斑狼疮（SLE）患者眼部病变发生病毒感染的临床特点和危险因素。方法分析SLE眼部病毒感染患者（13例，感染组）和无感染的SLE眼病患者（34例，无感染组），比较两组患者眼部受累局部表现、临床特点及糖皮质激素和／或免疫抑制剂用量，并对SLE眼部病毒感染的危险因素进行分析。结果①感染组眼部表现以结膜炎、角膜炎为主，而非感染组主要以视网膜渗出／出血、玻璃体混浊、视神经炎为主；②贫血、低白蛋白、低C3及大剂量激素和免疫抑制剂使用合并病毒感染的相对危险性增高。结论SLE眼部病毒感染与SLE本病眼部受累者临床表现不同，眼部病毒感染与激素用量和免疫抑制剂的使用有关。
Objective To investigate the risk factors for systemic Lupus Erythematosus（SLE） patients to develop eye viral infection. Methods Forty-seven lupus patients with eye involvements were involved in this study,including thirteen patients with eye viral infections （ infection group） and thirty-four patients without eye viral infection（ non-infection group）. Clinical features were compared between these tow groups and risk factors were analyced. Results Conjunctivitis and Keratitis were the most common manifestations in infection group while Exudative retinal / hemorrhage, Vitreous opacities, Optic neuritis. Anemia, Lypoalbuminemia, low level of C3 and high dose corticosteroid and/or immunosuppressive reagents predispose lupus patients to develop eye viral infection. Conclusion Clinical manifestations of eye viral infection in lupus patients are different from eye involvement due to lupus itself, high dose corticostened and/or immunosuppressive reagents are risk factor for lupus patients to develop eye viral infections.
出处
《中国临床实用医学》
2009年第4期26-28,共3页
China Clinical Practical Medicine
关键词
系统性红斑狼疮
眼病
病毒感染
危险因素
Systemic Lupus Erythematosus
Eye disease
Infected virus
Relative risk
