摘要
目的探讨彩超在经皮无水酒精注射(PEI)和经皮高温蒸馏水注射(PHDI)介入治疗肝细胞癌(HCC)的应用价值。方法40例HCC患者分为PEIT20例、PHDI20例,两组在病情、病程、病变程度、分类、年龄、性别、肿瘤大小和肿块数等方面无显著差异。所有病例于治疗前1天、治疗后1周、2周、1个月分别接受彩超检查,观察肿瘤的大小变化,检测肿瘤周边及内部的血流信息。结果PEIT和PHDI治疗前后肿瘤直径减小差异均有显著统计学意义(P<0.001,P<0.01),PEIT治疗后肿瘤直径减小与PHDI比较差异也有统计学意义(P<0.05);两组治疗前后肿瘤血供均有显著变化(P<0.05)。结论PEIT和PHDI均能明显减少肿瘤内部血供,PEIT治疗后肿瘤直径缩小较PHDI明显。彩超能准确地显示介入治疗后肿瘤大小的改变和肿瘤内部血供的变化,实时监控介入治疗过程,对疗效进行评估。
Objective To assess the value of color Doppler ultrasonography in interventional treatment of hepatocellular carcinoma （HCC） with percutaneous injection of ethanol （PEI） and percutaneous hyperthermal distilled-water injection （PHDI）. Methods Forty patients with HCC were divided into two groups. Each group had 20 patients and was treated by percutaneous injection of ethanol （PEI） and hyperthermal distilled-water （PHDI）, respectively. There was no significant difference between age, sex, grade, history, and size of tumor in two groups. Color Doppler ultrasonography was per- formed in all patients one day before treatment, one, two, and 4 weeks after treatment,respectively, and the size and de- gree of blood flow in all lesions were observed. Results There was significant difference in diameter of the tumors pre- treatment and post-treatment in PEIT group （P〈0. 001）, and in PHDI group （P〈0.01）. The mean diameter of PEIT group was smaller than that of PHDI group after treatment （P〈0. 05）. There was a significant difference in blood flow of the tumors pre-treatment and post-treatment in PEIT and PHDI group （both P〈0. 05）. Conclusion Blood flow of the HCC can be diminished with PEIT and PHDI. Color Doppler ultrasonography can detect interventional procedure in real- time, and make evaluation on the therapeutic effect.
出处
《中国介入影像与治疗学》
CSCD
2009年第2期103-106,共4页
Chinese Journal of Interventional Imaging and Therapy
基金
深圳市科技和信息局2008年科技计划(200803274)
关键词
超声检查
多普勒
彩色
癌
肝细胞
超声检查
介入性
Ultrasonography, Doppler, color
Carcinoma, hepatocellular
Ultrasonograhpy, interventional
