摘要
1例53岁接受腹膜透析的女性肾功能不全患者,因腹膜透析相关性隧道炎入院。给予氨曲南3g静脉滴注,2次/d;万古霉素0.125g加入腹透液2000ml中腹腔注入,4次/d。次日患者出现心慌、胸闷、气短,颜面、颈、前胸皮肤出现充血性红斑并有针刺感。立即用新鲜透析液行腹腔灌洗,静脉给予地塞米松5mg,20min后症状缓解,次日充血性红斑消失。停用万古霉素,改用替考拉宁腹透治疗,氨曲南治疗同前,患者无不良反应,1周后出院。
A 53-year-old woman with renal function insufficiency undergoing peritoneal dialysis was hospitalized with tunnel inflammation related to peritoneal dialysis. The woman received an IV infusion of aztreonam 3 g twice daily and an intraperitonal infusion of vancomyein 0. 125 g dissolved in 2 000 ml of peritoneal dialysate four times daily. The next day, she developed palpitation, chest distress, short breath, and congestive erythema with a prickling sensation on her face, neck, and chest. The peritoneal dialysate containing vancomycin was withdrawn immediately. The patient underwent peritoneal lavage with vacomycin-free dialysate and received Ⅳ dexamethasone 5 mg. Twenty minutes later, her symptoms resolved. The following day, her congestive erythema disappeared. Vancomyein was discontinued and switched to intraperitoneal teieoplanin. Aztreonam was continued with no adverse reactions. One week later, the patient completely recovered and was discharged.
出处
《药物不良反应杂志》
2009年第2期140-141,共2页
Adverse Drug Reactions Journal
关键词
万古霉素
腹腔灌注
红人综合征
不良反应
vancomycin
intraperitoneal infusion
red man syndrome
adverse reactions
