摘要
目的初步探讨慢性肾功能衰竭(CRF)中医证候特征。方法采用回顾性病例分析方法,对460例CRF患者的临床症状特点、中医证型特征、本虚证与标实证的相关性以及肾功能不同阶段、不同原发病与中医证型的相关性等进行分析。结果CRF前5位症状依次为倦怠乏力、面色晦暗、腰酸膝软、食少纳呆、气短懒言。CRF本虚证以脾肾气虚证为主,其次为气阴两虚证,阴阳两虚证最少;标实证以瘀血证为主,其次为湿浊证、水气证、湿热证,风动证最少;湿浊证、湿热证、水气证及风动证在本虚证型中分布不均衡(P<0.05),而瘀血证在本虚证型中分布均衡(P>0.05)。本虚证型在肾功能不同阶段分布不均衡(P<0.05);标实证型中,瘀血证及风动证在肾功能不同阶段分布不均衡(P<0.05),而湿浊证、湿热证及水气证分布均衡(P>0.05)。本虚证型在导致CRF的不同原发病之间分布均衡(P>0.05);标实证中,瘀血证、水气证及风动证在不同原发病之间分布不均衡(P<0.05),而湿浊证及湿热证分布均衡(P>0.05)。结论CRF的中医病机主要以脾肾气虚为本、瘀血证及湿浊证为标。
Objective To study the TCM syndrome characteristics of chronic renal failure （CRF）. Methods The retrospective analysis was made to analyze the correlation between the clinical manifestations, characteristics of TCM syndromes, Ben-deficiency syndrome and Biao-excess syndrome, and the correlation between different CRF stages, primary diseases, and TCM syndromes. Results The first five symptoms of CRF were： lassitude, dark complexion, soreness and weakness in the lumbus and legs, poor appetite, and shortness of breath. The Ben-deficiency syndrome was mainly Qi deficiency of spleen and kidney, then Qi and yin deficiency, and then both yin and yang deficiency; the Biao-excess syndrome was mainly blood stasis, then dampness, water retention, dampheat, and wind stirring. Distribution of syndromes of dampness, damp-heat, water retention, and wind stirring in Ben-deficiency was not balanced （P〈0.05）, while that of syndromes of blood stasis was balanced in Ben-deficiency （P〉0.05）. Distribution of Ben-deficiency syndromes was not balanced in different CRF stages （P〈0.05）. In Biao-excess, distribution of blood stasis and wind stirring syndromes was not balanced in different CRF stages （P〈0.05）, while distribution of dampness, damp-heat, and water retention syndromes was balanced （P〉0.05）. Ben-deficiency in causing the different primary diseases of CRF was balanced in distribution （P〈0.05）. In Biao-excess, distribution of blood stasis, water retention, and wind stirring syndromes in different primary diseases was not balanced （P〈0.05）, while distribution of dampness and damp-heat syndromes was balanced （P〉0.05）. Conclusion Qi deficiency of spleen and kidney is Ben-primary while blood stasis and dampness are Biao-secondary in the pathogenesis of CRF in TCM.
出处
《中医杂志》
CSCD
北大核心
2009年第5期446-448,共3页
Journal of Traditional Chinese Medicine
基金
中国中医科学院优势病种项目(CACMS05Y0019)
关键词
慢性肾功能衰竭
中医证型
辨证分析
诊法
Chronic renal failure （CRF）
TCM Syndrome
Syndrome differentiation
Diagnostic method
