摘要
糖尿病历来被认为是胰腺癌的危险因子,糖尿病患者发生胰腺癌者高于普通人群的2~3倍,但也有20%的胰腺癌患者在胰腺癌诊断前2年内已有糖尿病或糖耐量异常。糖尿病对胰腺癌是病因还是结果一直存有争议,本文对此作一剖析。
出处
《中华消化杂志》
CAS
CSCD
北大核心
2009年第5期359-360,共2页
Chinese Journal of Digestion
参考文献11
-
1Gullo I., Pezzilli R, Moselli-Labets AM. Diabetes and the risk of pancreatic cancer. N Engl J Med, 1994, 331:81-84.
-
2Gupta S, Viuinqhoff E, Bertenthal D, et al. New-onset diabetes and pancreatic cancer. Clin Gastroenterol Hepatol, 2006,4: 1366-1372.
-
3Chari ST, Leibson CL, Rabe KG, et al. Pancreatic cancer associated diabetes mellitus: prevalence and temporal associations witb diagnosis of cancer. Gastroenlerology, 2008, 134: 95-101.
-
4Ogawa Y, Tanaka M, Inoue K, et al. A prospective pancreatographic study of the prevalence of pancreatic carcinoma in patients with diabetes meliitus. Cancer, 2002, 94: 2344-2349.
-
5Permert J, i.arsson J, Westmark GT, et al. Islet amyloid polypeplide in patients with pancreatic cancer and diabetes. N EnglJ Med. 1991, 330: 313-318.
-
6Permert J, I,arsson J, Fruin AB. et al. Islet hormone secretion in pancreatic cancer patients with diabetes. Pancreas. 1997, 15: 60-68.
-
7Basso D, Valerio A, Brigato L, et al. An unidentified pancreatic cancer cell product alters some intraeellular pathways o1 glucose metabolisnl in isolated rats hepatocyte. Pancreas,1997,15:132-138.
-
8Stevens R J, Roddam AW, Beral V. Pancreatic cancer in type 1 and young-onset diabetes: systematic review and metaanalysis. Br J Cancer, 2007, 96:507-509.
-
9Permert J, Ihse PI, Jorfeldt L, et al. Improved glucose metabolism after subtotal pancreatectomy for pancreatic canctr. Br J Surg,i993, 80: 1047-1052.
-
10Lankisch PG. Exocrine and endocrine function in the management of pancreatic cancer// Neopolemos JP, Lemoine NR. Pancreatic Cancer. Molecular and Clinical Advances. Oxford. Blackwell Publishing Company, 1996:279-280.
同被引文献23
-
1Burke CA.Colonic complications of obesity.Gastroenterol Clin North Am,2010,39:47-55.
-
2Diehl AM.Hepatic complications of obesity.Gastroenterol Clin North Am,2010,39:57-68.
-
3Ratziu V,Poynard T.Hepatocellular carcinoma in NAFLD.In:Farrell GC,George J,de la Hall MP,Eds.Fatty liver diseases:NASH and related disorders.Blackwell Pub,2005,265-271.
-
4Kalli KR,Falowo OI,Bale LK,et al.Functional insulin receptors on human epithelial ovarian carcinoma cells:implications for IGF-Ⅱ mitogenic signaling.Endocrinology,2002,143:3259-3267.
-
5Macaulay VM.Insulin-like growth factors and cancer.Br J Cancer,1992,65:311-320.
-
6Nishiyama M,Wands JR.Cloning and increased expression of an insulin receptor substrate-1 like gene in human hepatocellular carcinoma.Biochem Biophys Res Commun,1992,183:280-285.
-
7Tanaka S,Wands JR.A carboxy-terminal truncaled insulin receptor substrate dominant negative protein reverses the human hepatocellular carcinoma malignant phenotype.J Clin Invest,1996,98:2100-2108.
-
8Bach LA,Rechler MM.Insulin-like growth factors and diabetes.Diabetes Metab Rev,1992,8:229-257.
-
9Scharf JG,Dombrowski F,Ramadori G.The IGF axis and hepatocarcinogenesis.Mol Pathol,2001,54:138-144.
-
10Chan JM,Stampfer MJ,Giovannucci E,et al.Plasma insulinlike growth factor-1 and prostate cancer risk:a prospective study.Science,1998,279:563-566.
-
1王庆学,王朝辉.内镜检查对胰腺癌诊断的体会[J].中华腹部疾病杂志,2001,1(5):433-434.
-
2钱璞,卢志贤,杨春香.胰腺癌患者血浆PAI-1测定的临床意义[J].放射免疫学杂志,2012,25(5):559-560. 被引量:2
-
3黄希芬.血糖在胰腺癌诊断中的探讨[J].中国实用医药,2008,3(16):75-76. 被引量:3
-
4吴建新,孟祥军,李定国,陆汉明.糖代谢异常与胰腺癌的早期临床表现[J].中华医学杂志,2002,82(5):312-314. 被引量:7
-
5万汝根,陈德宝,楼永刚,王茂峰,张巧红,金丹霞,周笋洪.血清血管生成素2水平在胰腺癌诊断中的价值[J].中华肿瘤杂志,2011,33(1):47-49. 被引量:4
-
6冯阳宁.多种MRI检查技术在胰腺癌诊断中的应用价值[J].中外医学研究,2013,11(9):51-52. 被引量:2
-
7汪俊伶,闵晓霞.联合检测多肿瘤标志物在胰腺癌诊断中的意义[J].标记免疫分析与临床,2016,23(4):418-420. 被引量:5
-
8陈首名,马方伟,李光纪,左斌,何志兵,罗鹰.磁共振弥散加权成像联合动态增强扫描在胰腺癌诊断中的应用价值[J].西部医学,2013,25(1):123-124. 被引量:4
-
9彭林,王卫东,陈盛.检测胰液中K-ras基因突变对胰腺癌诊断的作用[J].实用医学杂志,2006,22(18):2109-2111. 被引量:4
-
10孟庆才,古宏晨,黄新余.微小RNA在胰腺癌诊疗中的研究进展[J].国际肿瘤学杂志,2014,41(11):837-840. 被引量:1