摘要
目的 观察大黄提取液对脱矿釉质中钙溶出量的影响。方法 用不同浓度的大黄提取液和去离子水处理牙面后进行脱矿，ASCA生化分析仪对釉质脱矿后的脱矿液进行钙离子浓度的检测。结果 2mg／ml和4mg／ml大黄提取液处理后釉质钙溶出量〈去离子水（P〈0．01）、〈1mg／ml大黄提取液组（P〈0．05），〉2％氟化钠组但差异无统计学意义（P〉0．05）。1mg／ml大黄提取液处理后釉质钙溶出量〉2％氟化钠组（P〈0．01），〈去离子水组但差异无统计学意义（P〉0．05）。结论 2mg／ml和4mg／ml大黄提取液具有抑制脱矿釉质中钙溶出作用；2mg／ml大黄提取液为抑制钙溶出的起始有效浓度。
Objective To observe effects of rhubarb extract on Ca dissolved quantity in demineralized enamel. Methods Demineralization was performed after treating tooth facing with rhubarb extract of different concentrations and deionized water. The concentration of Ca was detected by ASCA biochemical analyzer after deminetalization. Results Dissolved quantity of deminenralized Ca in the rhubarb extract group （2 mg/ml, 4 mg/ml） was significantly lower than that of the deionized water group （P〈0.01） and the rhubarb extract group （1 mg/ml） （P〈0.05）, but higher than that of 2% sodium fluoride group （P〉0.05）. Dissolved quantity of demineralized Ca in the rhubarb extract （ 1 mg/ml） group was significantly higher than that of 2% sodium fluoride group （P〈0.01 ）, but lower than that of the deionized water group（P〉0.05）.Conclusion The rhubarb extract （2mg/ml, 4mg/ml） can inhibit Ca dissolution in demineralized enamel. The initial effective concentration of rhubarb extract is 2 mg/ml.
出处
《国际中医中药杂志》
2009年第3期221-222,共2页
International Journal of Traditional Chinese Medicine
基金
黑龙江省卫生厅科研课题（项目编号：2007-041）
关键词
大黄
脱矿
氟
人工釉质龋
ASCA生化分析仪
Rhubarb： Demineralization
Fluorine
Artificial enamelcaries
ASCA biochemical analyzer
