摘要
目的：探讨高压氧治疗对血管性痴呆大鼠学习、记忆功能的影响。方法：采用Ｐｕｌｓｉｎｅｌｉ氏血管闭塞改良法建立大鼠血管性痴呆动物模型。用高压氧进行治疗，水迷宫和跳台试验观察痴呆大鼠治疗前后学习、记忆功能的变化。结果：ＨＢＯ１组和ＨＢＯ２组，经过２０次高压氧治疗后，其在水迷宫和跳台试验中的成绩比未治疗组有明显提高。结论：高压氧治疗对血管性痴呆大鼠学习、记忆功能有改善作用。
Objective: To investigate the effects of hyperbaric oxygen therapy on learning and memoryfunction in rats suffering from vascular dementia. Method: Pulsinelli vesselocclusion method was adopted to establish a model of vascular dementia in SD rats which were subsequently treated with hyperbaric oxygen. Learning and memory functions were evaluated by the Water Maze Test and Step Down Test before and after treatment.Results: After 20 times hyperbaric oxygen therapy, group HBO1 and HBO2 showed better improvement in Water Maze Test and Step Down Test than the control group. Conclusion: hyperbaric oxygen therapy can improve learning and memory function in rats suffering from vascular dementia.
出处
《中国临床心理学杂志》
CSCD
1998年第2期81-84,共4页
Chinese Journal of Clinical Psychology
关键词
血管性痴呆
大鼠
学习
记忆
高压氧
Vascular dementia, Rat, Learning, Memory, Hyperbaric oxygen
