摘要
目的探讨急性脑梗死患者血浆纤维蛋白原与D-二聚体水平的变化及其临床意义。方法分别应用Clauss法及乳胶免疫比浊法检测96例急性脑梗死患者及30例健康对照者血浆纤维蛋白原和D-二聚体水平。结果急性脑梗死组血浆纤维蛋白原和D-二聚体水平明显高于对照组(P<0.05),且随着急性脑梗死严重程度的增加,血浆纤维蛋白原和D-二聚体水平逐渐增高(P<0.05)。急性脑梗死患者血浆纤维蛋白原水平与D-二聚体水平呈显著正相关(r=0.423,P<0.05)。结论脑梗死患者血浆纤维蛋白原和D-二聚体水平变化对判断脑梗死的发生及病情轻重具有重要的意义。
Aim To discuss the changes and significance of plasma fibrinogen and D-dimer in patients with acute cerebral. Methods The levels of plasma fibrinogen and D-dimer in 96 cases of acute cerebral infarction and 30 healthy controls were detected with Clauss method and immunoturbidimetry method, respectively. Results The levels of plasma fibrinogen and D-dimer were significantly higher than those in the control group （P〈0.05）. Moreover, with the aggression of acute cerebral infarction, the levels of fibrinogen and D-dimer were increasing, gradually （P〈0.05）. The levels of fibrinogen were positively correlated with the levels of D-dimer （r=0.423, P〈0.05）. Conclusion The levels of plasma fibrinogen and D-dimer are useful for the diagnosis and evaluation of disease severity.
出处
《中国动脉硬化杂志》
CAS
CSCD
北大核心
2009年第4期321-322,共2页
Chinese Journal of Arteriosclerosis
