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美托洛尔注射液与西地兰控制快速心房颤动的疗效比较 被引量:8

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摘要 目的观察静脉用美托洛尔与毛花甙C(西地兰)控制快速心房颤动(房颤)心室率的疗效和安全性。方法将70例快速房颤患者随机分为两组,美托洛尔组36例,稀释后缓慢静脉注射美托洛尔5mg,观察5分钟,如无效重复1次,连续用药3次,总量15mg;西地兰组34例,稀释后缓慢静脉注射西地兰0.4mg,观察10分钟,如无效追加0.2mg,连续用药3次,总量0.8mg。记录用药前后心室率和血压变化,比较在各观察时间点上的有效率。结果平均起效时间美托洛尔组[(10.1±7.6)分钟]较西地兰组[(40.8±12.4)分钟]明显缩短,心室率下降幅度美托洛尔组(36.5%)较西地兰组(26.3%)明显增大,在60分钟内各观察时间点的治疗有效率美托洛尔组(47%、69%、83%、91%)明显高于西地兰组(9%、15%、35%、59%),均无严重不良反应发生。结论美托洛尔注射液较西地兰控制快速房颤心室率更快速、有效、安全。
出处 《临床内科杂志》 CAS 2009年第6期414-416,共3页 Journal of Clinical Internal Medicine
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