摘要
目的了解艾滋病抗病毒治疗患者生活质量的现状并分析其相关因素。方法应用SF-36量表评价758例艾滋病抗病毒治疗患者的生活质量，同时调查可能影响生活质量的人口学特征和与HIV感染相关的特征。采用t检验、方差分析进行均数显著性检验，采用多元线性回归模型分析艾滋病抗病毒治疗患者生活质量生理健康总分和心理健康总分的相关因素。结果758例艾滋病抗病毒治疗患者生理健康总分45．34±8．77，心理健康总分41．92±12．01。患者年龄越小生理健康总分越高，心理健康总分则越低。抗病毒治疗时间越长心理健康总分越低。男性、血CD4^＋T淋巴细胞计数水平高的患者生理和心理健康总分比女性、血CD4^＋T淋巴细胞计数水平低的患者得分高。性途径、静脉吸毒途径和其他途径或尚不明确途径感染生理和心理健康总分高于单采血浆途径。结论应加强对年龄较小、女性、单采血浆感染、血CD4^＋T淋巴细胞计数水平低、抗病毒治疗时间较长的艾滋病感染者或患者的心理健康辅导，以提高其生活质量。
Objective Studing the main influencing risk factors to provide evidence for improving the quality of life among people living with HIV. Methods The quality of life on 758 patients with HIV was evaluated by the Medical Outcomes Study Short-Form Health Survey （SF-36） and some potential risk factors as personal characteristics and disease condition were studied. Means and standard deviations of data were calculated and differences among groups and variances were tested using Student＇ s t test, followed by step-wise multivariate regression. Results The SF-36 two summary scores of 758 patients with HIV appeared to be 45.34± 8.77 and 41.92±12.01 respectively. The physical component summary scores （PCS） had a gradual decrease with the increase of age. However, mental component summary scores （MCS） had a gradual decrease with the increase of time receiving the treatment. Male patients reported having a better quality of life （QOL） than female, and patients who were infected through injecting drug use and sexual transmission reported to have had better QOL than patients who were infected through paid blood plasma donation. Compare to patients having low CD4^ ＋ count, those having higher CD4^＋ count reported to have better QOL. Conclusion Patients being young, female, infected through paid blood plasma donation, having low CD4^＋ count, or treated for longer period, would have unsatisfactory QOL.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2009年第6期622-625,共4页
Chinese Journal of Epidemiology
基金
卫生部艾滋病防治应用性研究项目（WA-2006-03）
关键词
艾滋病
生活质量
相关因素
AIDS
Quality of life
Influencing factors
