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血尿酸与急性冠状动脉综合征367例的相关性研究 被引量：3

Relationship between serum level of uric acid and acute coronary syndromes
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摘要 目的探讨血清尿酸(SUA)水平与急性冠状动脉综合征(ACS)的相关性。方法经临床确诊的冠心病(CHD)患者182例[其中慢性稳定型(A组)94例,ACS(B组)88例]与对照组185例。分别测定SUA及血脂。结果ACS组SUA水平显著高于对照组(P<0.01),Logistic回归分析显示,SUA增高与ACS明显相关。结论高尿酸血症是ACS的主要危险因素之一。 Objective To explore the co, elation between serum level of uric acid and acute coronary syndromes （ACS）. Methods One hundred and eighty two patients with CHD eonftrmed by angiography and 185 control subjects without CHD were included in this study, and serum level of uric acid and blood lipids were determined. Results Serum level of uric acid in ACS patients was markedly higher than that of control subjects （ P 〈0.01 ）. Analysis with multivariate Logistic, SUA has obvious relationship with ACS. Condusion Elevated serum level of uric acid is one of the main risk factors for pathogenesis of ACS.
作者 廖成标 吴伦宽 蒋爱忠 孙永红
机构地区 河源市人民医院心内科 贵阳医学院附院心内科 广州市第十一人民医院内科
出处 《临床和实验医学杂志》 2009年第6期77-77,79,共2页 Journal of Clinical and Experimental Medicine
关键词 尿酸 急性冠状动脉综合征 危险因素 Serum Uric Acid Acute Coronary Syndromes Risk factors
分类号 R541.4 [医药卫生—心血管疾病]
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  • 1冯波,李栩,黄亦文,乐秀康,富明,陈明慧,戴明德,倪亚芳,赵竹芳,周凤英,孟仲莹,王惠玲,姚国良,张容,刘昊,张小倩.上海市浦东新区社区人群代谢综合征状况和相关危险因素分析[J].中华内分泌代谢杂志,2004,20(3):231-232. 被引量：34
  • 2叶任高.内科学 :第5版[M].北京：人民卫生出版社,2001.280.
  • 3Gorter PM, Olijhoek JK, van der Graaf Y, et al. Prevalence of the metabolic syndrome in patients with coronary heart disease, cerebrovascular disease, peripheral arterial disease or abdominal aortic aneurysm. Atherosclerosis, 2004,173:363-369.
  • 4Fang J, Alderman MH. Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey. JAMA, 2000,283:2404-2410.
  • 5Nieto FJ, Iribarren C, Gross MD, et al. Uric acid and serum antioxidant capacity: a reaction to atherosclerosis? Atherosclerosis, 2000,148:131-139.
  • 6Conen D, Wietlisbach V, Bovet P, et al. Prevalence of hyperuricemia and relation of serum uric acid with cardiovascular risk factors in a developing country. BMC Public Health, 2004,4:9.
  • 7Costa A, Iguala I, Bedini J, et al. Uric acid concentration in subjects at risk of type 2 diabetes mellitus: relationship to components of the metabolic syndrome. Metabolism, 2002,51:372-375.
  • 8Bickel C, Rupprocht HJ, Blankenberg S, et al. Serum uric acid as an independent predicotor of mortality in patients with angiographically proven coronary artery disease. Am J Cardiol, 2002, 89(1):12-17.
  • 9Jing Fang, Michael H, Alderman. Serum uric acid and cardiovascular mortality. JAMA, 2000, 283:2404-2410.
  • 10Niskanen IX, Laaksonen DE, Nyyssonen K, et al. Uric acid level as a risk factor for cardiovascular and all-cause mortality in middle-aged men: a prospective cohort study. Arch Intern Med, 2004, 164(14):1546-1551.

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同被引文献25

  • 1曾凡源,杨平珍.C反应蛋白与急性冠状动脉综合征的相关性研究[J].河北医学,2005,11(5):428-430. 被引量：1
  • 2急性心肌梗死诊断和治疗指南(摘登)[J].新医学,2006,37(1):46-46. 被引量：25
  • 3Kanellis J, Watanabe S, Li JH, et al. Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2 [J]. Hypertension, 2003,41:1287-1293.
  • 4Longo-Mbenza B, Luila EL, Mbete P, et al. Is hyperuricemia a risk factor of stroke and coronary heart disease among Mricans?[J]. Int J Cardiol, 1999,71:17-22.
  • 5Leyva F, Anlcer S, Swan JW, et al. Serum uric acid as an index of impaired oxidative metabolism in chronic heart failure[J]. Eur Heart J, 1997,18:858-865.
  • 6Suwanwela N C, Chutinetr A. Risk factors for atherosclero- sis of cervicocerebral arteries; intracranial versus extracraninl [J]. neuroepidemiology, 2003, 22: 37.
  • 7Rosa E M Kramer C. Castrol association between coronary artery artery atherosclerosis and the intimar media thickeness of the common carotid artery measured on ultrasonography [J]. Arq Bras Cardiol, 2003, 80: 589.
  • 8Kanellis J, Watanabe S, Li J H, et al. Uric acid stimulates monocyte chemoattractant protein-1 produation in vascular .smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2 [J]. Hypertension, 2003, 41: 1287.
  • 9Leyva F, Anlcer S, Swan J W, et al. Serum uric acid as an index of impaired oxidative metabolism in chronic heart failure [J]. Eur Heart J, 1997, 18: 858.
  • 10Cerrato, Imperiale. Higher Lipoprotein ( a ) lever in atheothrombotic than lacunar ischemic cerebrovascluar disease[J]. Neurology, 2002, 58: 653.

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临床和实验医学杂志
2009年 第6期

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