摘要
目的研究氯诺昔康不同用药时机对腹腔镜术后急性疼痛的治疗效果。方法将120例ASAⅠ、Ⅱ级择期行腹腔镜手术的患者,随机分为3组:A组,切皮前静脉注射氯诺昔康16mg;B组,手术结束后静脉注射氯诺昔康16mg;C组为对照组;每组40例。3组分别于术后0.5、1、2、6、12和24h进行视觉模拟评分(VAS)并记录术后镇痛药的使用、不良反应发生情况。结果腹腔镜手术患者切皮前及手术结束后静脉注入氯诺昔康16mg均可使VAS显著降低,且无明显不良反应。切皮前用药组VAS低于手术结束后用药组(P<0.01)。结论氯诺昔康术前、术后使用对腹腔镜术后急性疼痛均有治疗效果,切皮前用药效果优于手术结束后用药。
[Objective] To study the analgesia effects of lomoxicam administrated at different time on acute postoperative pain in patients undergoing laparoseopie operation. [Methods] One hundred and twenty patients undergoing laparoscopic operation were randomly divided into three groups with 40 cases in each, The patients in group A received lornoxicam 16 mg before operation, and in group B lornoxicam 16 mg were given after operation, and in group C equivalent dose of 0.9% NaCl was injected as control. The pain score with visual analogue scale （VAS）, the effects of the analgesic, incidence of adverse effects were recorded in all the eases at the emergence from anesthesia, 0.5, 1, 2, 6, 12 and 24 hours after the emergence. [Results] Both preoperative and postoperative intravenous injection of 16 mg lornoxicam could markedly reduce VAS. VAS was lower in group A than that in group B （P 〈0.05）. [ Conclusion] Lomoxieam administered before or after operation may relieve postoperative pain in patients undergoing laparoscopic surgery with a few side-effects. It is more effective to inject lornoxicam before operation than after operation.
出处
《中国内镜杂志》
CSCD
北大核心
2009年第5期505-506,509,共3页
China Journal of Endoscopy
